Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liv...
Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis
About this item
Full title
Author / Creator
Letouzé, Eric , Shinde, Jayendra , Renault, Victor , Couchy, Gabrielle , Blanc, Jean-Frédéric , Tubacher, Emmanuel , Bayard, Quentin , Bacq, Delphine , Meyer, Vincent , Semhoun, Jérémy , Bioulac-Sage, Paulette , Prévôt, Sophie , Azoulay, Daniel , Paradis, Valérie , Imbeaud, Sandrine , Deleuze, Jean-François and Zucman-Rossi, Jessica
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Genomic alterations driving tumorigenesis result from the interaction of environmental exposures and endogenous cellular processes. With a diversity of risk factors, liver cancer is an ideal model to study these interactions. Here, we analyze the whole genomes of 44 new and 264 published liver cancers and we identify 10 mutational and 6 structural...
Alternative Titles
Full title
Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis
Authors, Artists and Contributors
Author / Creator
Shinde, Jayendra
Renault, Victor
Couchy, Gabrielle
Blanc, Jean-Frédéric
Tubacher, Emmanuel
Bayard, Quentin
Bacq, Delphine
Meyer, Vincent
Semhoun, Jérémy
Bioulac-Sage, Paulette
Prévôt, Sophie
Azoulay, Daniel
Paradis, Valérie
Imbeaud, Sandrine
Deleuze, Jean-François
Zucman-Rossi, Jessica
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a2db6282c9e94e1b953a8aca7a20d3f7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2db6282c9e94e1b953a8aca7a20d3f7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01358-x
