Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary scle...
Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis
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Author / Creator
The International PSC Study Group , International PSC Study Group , Han, Younghun , Byun, Jinyoung , Zhu, Catherine , Sun, Ryan , Roh, Julia Y. , Cordell, Heather J. , Lee, Hyun-Sung , Shaw, Vikram R. , Kang, Sung Wook , Razjouyan, Javad , Cooley, Matthew A. , Hassan, Manal M. , Siminovitch, Katherine A. , Folseraas, Trine , Ellinghaus, David , Bergquist, Annika , Rushbrook, Simon M. , Franke, Andre , Karlsen, Tom H. , Lazaridis, Konstantinos N. , McGlynn, Katherine A. , Roberts, Lewis R. and Amos, Christopher I.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Primary sclerosing cholangitis (PSC) is a rare autoimmune bile duct disease that is strongly associated with immune-mediated disorders. In this study, we implemented multitrait joint analyses to genome-wide association summary statistics of PSC and numerous clinical and epidemiological traits to estimate the genetic contribution of each trait and g...
Alternative Titles
Full title
Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis
Authors, Artists and Contributors
Author / Creator
International PSC Study Group
Han, Younghun
Byun, Jinyoung
Zhu, Catherine
Sun, Ryan
Roh, Julia Y.
Cordell, Heather J.
Lee, Hyun-Sung
Shaw, Vikram R.
Kang, Sung Wook
Razjouyan, Javad
Cooley, Matthew A.
Hassan, Manal M.
Siminovitch, Katherine A.
Folseraas, Trine
Ellinghaus, David
Bergquist, Annika
Rushbrook, Simon M.
Franke, Andre
Karlsen, Tom H.
Lazaridis, Konstantinos N.
McGlynn, Katherine A.
Roberts, Lewis R.
Amos, Christopher I.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a3158eab38c04ddbaa6e7834c504e9f6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a3158eab38c04ddbaa6e7834c504e9f6
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-36678-8
