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A predictive index for health status using species-level gut microbiome profiling
Author / Creator:Gupta, Vinod K. ; Kim, Minsuk ; Bakshi, Utpal ; Cunningham, Kevin Y. ; Davis, John M. ; Lazaridis, Konstantinos N. ; Nelson, Heidi ; Chia, Nicholas ; Sung, Jaeyun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-09, Vol.11 (1), p.4635-4635, Article 4635
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The Cholangiopathies
Author / Creator:Lazaridis, Konstantinos N., MD ; LaRusso, Nicholas F., MD
Publisher:England: Elsevier Inc
Journal title:Mayo Clinic proceedings, 2015-06, Vol.90 (6), p.791-800
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A scalable workflow to characterize the human exposome
Author / Creator:Hu, Xin ; Walker, Douglas I. ; Liang, Yongliang ; Smith, Matthew Ryan ; Orr, Michael L. ; Juran, Brian D. ; Ma, Chunyu ; Uppal, Karan ; Koval, Michael ; Martin, Greg S. ; Neujahr, David C. ; Marsit, Carmen J. ; Go, Young-Mi ; Pennell, Kurt D. ; Miller, Gary W. ; Lazaridis, Konstantinos N. ; Jones, Dean P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-09, Vol.12 (1), p.5575-12, Article 5575
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Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis
Author / Creator:Han, Younghun ; Byun, Jinyoung ; Zhu, Catherine ; Sun, Ryan ; Roh, Julia Y. ; Cordell, Heather J. ; Lee, Hyun-Sung ; Shaw, Vikram R. ; Kang, Sung Wook ; Razjouyan, Javad ; Cooley, Matthew A. ; Hassan, Manal M. ; Siminovitch, Katherine A. ; Folseraas, Trine ; Ellinghaus, David ; Bergquist, Annika ; Rushbrook, Simon M. ; Franke, Andre ; Karlsen, Tom H. ; Lazaridis, Konstantinos N. ; McGlynn, Katherine A. ; Roberts, Lewis R. ; Amos, Christopher I.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-02, Vol.14 (1), p.1069-13, Article 1069
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Predicting cholangiocarcinoma in primary sclerosing cholangitis: using artificial intelligence, clinical and laboratory data
Author / Creator:Hu, Chang ; Iyer, Ravishankar K ; Juran, Brian D ; McCauley, Bryan M ; Atkinson, Elizabeth J ; Eaton, John E ; Ali, Ahmad H ; Lazaridis, Konstantinos N
Publisher:England: BioMed Central Ltd
Journal title:BMC gastroenterology, 2023-04, Vol.23 (1), p.129-129, Article 129
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An update on primary sclerosing cholangitis epidemiology, outcomes and quantification of alkaline phosphatase variability in a population-based cohort
Author / Creator:Bakhshi, Zeinab ; Hilscher, Moira B. ; Gores, Gregory J. ; Harmsen, William S. ; Viehman, Jason K. ; LaRusso, Nicholas F. ; Gossard, Andrea A. ; Lazaridis, Konstantinos N. ; Lindor, Keith D. ; Eaton, John E.
Publisher:Singapore: Springer Singapore
Journal title:Journal of gastroenterology, 2020-05, Vol.55 (5), p.523-532
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Diagnostic yield of exome and genome sequencing after non-diagnostic multi-gene panels in patients with single-system diseases
Author / Creator:Wilke, Matheus V M B ; Klee, Eric W ; Dhamija, Radhika ; Fervenza, Fernando C ; Thomas, Brittany ; Leung, Nelson ; Hogan, Marie C ; Hager, Megan M ; Kolbert, Kayla J ; Kemppainen, Jennifer L ; Loftus, Elle C ; Leitzen, Katie M ; Vitek, Carolyn R ; McAllister, Tammy ; Lazaridis, Konstantinos N ; Pinto E Vairo, Filippo
Publisher:England: BioMed Central Ltd
Journal title:Orphanet journal of rare diseases, 2024-05, Vol.19 (1), p.216-216, Article 216
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Primary Sclerosing Cholangitis
Author / Creator:Lazaridis, Konstantinos N ; LaRusso, Nicholas F
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2016-09, Vol.375 (12), p.1161-1170
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Individualized Medicine in Gastroenterology and Hepatology
Author / Creator:Stephens, Michael C., MD ; Boardman, Lisa A., MD ; Lazaridis, Konstantinos N., MD
Publisher:England: Elsevier Inc
Journal title:Mayo Clinic proceedings, 2017-05, Vol.92 (5), p.810-825
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The PSC scientific community resource: an asset for multi-omics interrogation of primary sclerosing cholangitis
Author / Creator:Ali, Ahmad Hassan ; Juran, Brian D ; Schlicht, Erik M ; Bianchi, Jackie K ; McCauley, Bryan M ; Atkinson, Elizabeth J ; Lazaridis, Konstantinos N
Publisher:England: BioMed Central Ltd
Journal title:BMC gastroenterology, 2021-09, Vol.21 (1), p.353-353, Article 353
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Evaluation of circulating cell-free DNA in cholestatic liver disease using liver-specific methylation markers
Author / Creator:Punia, Sohan ; Juran, Brian D ; Ali, Ahmad H ; Schlicht, Erik M ; Moore, Raymond M ; Sun, Zhifu ; Lazaridis, Konstantinos N
Publisher:England: BioMed Central Ltd
Journal title:BMC gastroenterology, 2021-04, Vol.21 (1), p.149-149, Article 149
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ArticlesPeer ReviewedFull Text
Biochemical response to ursodeoxycholic acid predicts survival in a North American cohort of primary biliary cirrhosis patients
Author / Creator:Lammert, Craig ; Juran, Brian D. ; Schlicht, Erik ; Chan, Landon L. ; Atkinson, Elizabeth J. ; de Andrade, Mariza ; Lazaridis, Konstantinos N.
Publisher:Tokyo: Springer Japan
Journal title:Journal of gastroenterology, 2014-10, Vol.49 (10), p.1414-1420
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High‐Resolution Exposomics and Metabolomics Reveals Specific Associations in Cholestatic Liver Diseases
Author / Creator:Walker, Douglas I. ; Juran, Brian D. ; Cheung, Angela C. ; Schlicht, Erik M. ; Liang, Yongliang ; Niedzwiecki, Megan ; LaRusso, Nicholas F. ; Gores, Gregory J. ; Jones, Dean P. ; Miller, Gary W. ; Lazaridis, Konstantinos N.
Publisher:United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
Journal title:Hepatology communications, 2022-05, Vol.6 (5), p.965-979
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Algebraic topology-based machine learning using MRI predicts outcomes in primary sclerosing cholangitis
Author / Creator:Singh, Yashbir ; Jons, William A. ; Eaton, John E. ; Vesterhus, Mette ; Karlsen, Tom ; Bjoerk, Ida ; Abildgaard, Andreas ; Jorgensen, Kristin Kaasen ; Folseraas, Trine ; Little, Derek ; Gulamhusein, Aliya F. ; Petrovic, Kosta ; Negard, Anne ; Conte, Gian Marco ; Sobek, Joseph D. ; Jagtap, Jaidip ; Venkatesh, Sudhakar K. ; Gores, Gregory J. ; LaRusso, Nicholas F. ; Lazaridis, Konstantinos N. ; Erickson, Bradley J.
Publisher:Vienna: Springer Vienna
Journal title:European radiology experimental, 2022-11, Vol.6 (1), p.58-9, Article 58
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Induced Pluripotent Stem Cells From Subjects With Primary Sclerosing Cholangitis Develop a Senescence Phenotype Following Biliary Differentiation
Author / Creator:Jalan‐Sakrikar, Nidhi ; De Assuncao, Thiago M. ; Navarro‐Corcuera, Amaia ; Hamdan, Feda H. ; Loarca, Lorena ; Kirkeby, Lindsey A. ; Resch, Zachary T. ; O’Hara, Steven P. ; Juran, Brian D. ; Lazaridis, Konstantinos N. ; Rosen, Charles B. ; Heimbach, Julie K. ; Taner, Timucin ; Shah, Vijay H. ; LaRusso, Nicholas F. ; Huebert, Robert C.
Publisher:United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
Journal title:Hepatology communications, 2022-02, Vol.6 (2), p.345-360
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Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers
Author / Creator:Borad, Mitesh J. ; Egan, Jan B. ; Condjella, Rachel M. ; Liang, Winnie S. ; Fonseca, Rafael ; Ritacca, Nicole R. ; McCullough, Ann E. ; Barrett, Michael T. ; Hunt, Katherine S. ; Champion, Mia D. ; Patel, Maitray D. ; Young, Scott W. ; Silva, Alvin C. ; Ho, Thai H. ; Halfdanarson, Thorvardur R. ; McWilliams, Robert R. ; Lazaridis, Konstantinos N. ; Ramanathan, Ramesh K. ; Baker, Angela ; Aldrich, Jessica ; Kurdoglu, Ahmet ; Izatt, Tyler ; Christoforides, Alexis ; Cherni, Irene ; Nasser, Sara ; Reiman, Rebecca ; Cuyugan, Lori ; McDonald, Jacquelyn ; Adkins, Jonathan ; Mastrian, Stephen D. ; Valdez, Riccardo ; Jaroszewski, Dawn E. ; Von Hoff, Daniel D. ; Craig, David W. ; Stewart, A. Keith ; Carpten, John D. ; Bryce, Alan H.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-12, Vol.6 (1), p.25-12, Article 25
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Clinical Trials for Special Populations: Children, Older Adults, and Rare Diseases
Author / Creator:Jacobson, Robert M ; Pignolo, Robert J ; Lazaridis, Konstantinos N
Publisher:England: Elsevier, Inc
Journal title:Mayo Clinic proceedings, 2024-02, Vol.99 (2), p.318-335
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Pharmacogenomic findings from clinical whole exome sequencing of diagnostic odyssey patients
Author / Creator:Cousin, Margot A. ; Matey, Eric T. ; Blackburn, Patrick R. ; Boczek, Nicole J. ; McAllister, Tammy M. ; Kruisselbrink, Teresa M. ; Babovic‐Vuksanovic, Dusica ; Lazaridis, Konstantinos N. ; Klee, Eric W.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular genetics & genomic medicine, 2017-05, Vol.5 (3), p.269-279
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Genomic Medicine and Incidental Findings: Balancing Actionability and Patient Autonomy
Author / Creator:McCormick, Jennifer B., PhD, MPP ; Sharp, Richard R., PhD ; Farrugia, Gianrico, MD ; Lindor, Noralane M., MD ; Babovic-Vuksanovic, Dusica, MD ; Borad, Mitesh J., MD ; Bryce, Alan H., MD ; Caselli, Richard J., MD ; Ferber, Matthew J., PhD ; Johnson, Kiley J., CGC ; Lazaridis, Konstantinos N., MD ; McWilliams, Robert R., MD ; Murray, Joseph A., MD ; Parker, Alexander S., PhD ; Schahl, Kimberly A., CGC ; Wieben, Eric D., PhD
Publisher:England: Elsevier Inc
Journal title:Mayo Clinic proceedings, 2014-06, Vol.89 (6), p.718-721
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Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic
Author / Creator:Lazaridis, Konstantinos N., MD ; Schahl, Kimberly A., CGC ; Cousin, Margot A., PhD ; Babovic-Vuksanovic, Dusica, MD ; Riegert-Johnson, Douglas L., MD ; Gavrilova, Ralitza H., MD ; McAllister, Tammy M., MA ; Lindor, Noralane M., MD ; Abraham, Roshini S., PhD ; Ackerman, Michael J., MD, PhD ; Pichurin, Pavel N., MD ; Deyle, David R., MD ; Gavrilov, Dimitar K., MD, PhD ; Hand, Jennifer L., MD ; Klee, Eric W., PhD ; Stephens, Michael C., MD ; Wick, Myra J., MD, PhD ; Atkinson, Elizabeth J., MS ; Linden, David R., PhD ; Ferber, Matthew J., PhD ; Wieben, Eric D., PhD ; Farrugia, Gianrico, MD
Publisher:Elsevier Inc
Journal title:Mayo Clinic proceedings, 2016-03, Vol.91 (3), p.297-307
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A predictive index for health status using species-level gut microbiome profiling

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The Cholangiopathies

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A scalable workflow to characterize the human exposome

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Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis

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Predicting cholangiocarcinoma in primary sclerosing cholangitis: using artificial intelligence, clinical and laboratory data

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An update on primary sclerosing cholangitis epidemiology, outcomes and quantification of alkaline phosphatase variability in a population-based cohort

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Diagnostic yield of exome and genome sequencing after non-diagnostic multi-gene panels in patients with single-system diseases

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Primary Sclerosing Cholangitis

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Individualized Medicine in Gastroenterology and Hepatology

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The PSC scientific community resource: an asset for multi-omics interrogation of primary sclerosing cholangitis

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Evaluation of circulating cell-free DNA in cholestatic liver disease using liver-specific methylation markers

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Biochemical response to ursodeoxycholic acid predicts survival in a North American cohort of primary biliary cirrhosis patients

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High‐Resolution Exposomics and Metabolomics Reveals Specific Associations in Cholestatic Liver Diseases

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Algebraic topology-based machine learning using MRI predicts outcomes in primary sclerosing cholangitis

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Induced Pluripotent Stem Cells From Subjects With Primary Sclerosing Cholangitis Develop a Senescence Phenotype Following Biliary Differentiation

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Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

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Clinical Trials for Special Populations: Children, Older Adults, and Rare Diseases

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Pharmacogenomic findings from clinical whole exome sequencing of diagnostic odyssey patients

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Genomic Medicine and Incidental Findings: Balancing Actionability and Patient Autonomy

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Outcome of Whole Exome Sequencing for Diagnostic Odyssey Cases of an Individualized Medicine Clinic

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