Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation
Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation
About this item
Full title
Author / Creator
Tsuchiya, Masaki , Hara, Yuji , Okuda, Masaki , Itoh, Karin , Nishioka, Ryotaro , Shiomi, Akifumi , Nagao, Kohjiro , Mori, Masayuki , Mori, Yasuo , Ikenouchi, Junichi , Suzuki, Ryo , Tanaka, Motomu , Ohwada, Tomohiko , Aoki, Junken , Kanagawa, Motoi , Toda, Tatsushi , Nagata, Yosuke , Matsuda, Ryoichi , Takayama, Yasunori , Tominaga, Makoto and Umeda, Masato
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Myotube formation by fusion of myoblasts and subsequent elongation of the syncytia is essential for skeletal muscle formation. However, molecules that regulate myotube formation remain elusive. Here we identify PIEZO1, a mechanosensitive Ca
2+
channel, as a key regulator of myotube formation. During myotube formation, phosphatidylserine, a ph...
Alternative Titles
Full title
Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation
Authors, Artists and Contributors
Author / Creator
Hara, Yuji
Okuda, Masaki
Itoh, Karin
Nishioka, Ryotaro
Shiomi, Akifumi
Nagao, Kohjiro
Mori, Masayuki
Mori, Yasuo
Ikenouchi, Junichi
Suzuki, Ryo
Tanaka, Motomu
Ohwada, Tomohiko
Aoki, Junken
Kanagawa, Motoi
Toda, Tatsushi
Nagata, Yosuke
Matsuda, Ryoichi
Takayama, Yasunori
Tominaga, Makoto
Umeda, Masato
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a4b94536489a4c5abfb6db09652f9498
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4b94536489a4c5abfb6db09652f9498
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04436-w
