Network quantification of EGFR signaling unveils potential for targeted combination therapy
Network quantification of EGFR signaling unveils potential for targeted combination therapy
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The epidermal growth factor receptor (EGFR) signaling network is activated in most solid tumors, and small‐molecule drugs targeting this network are increasingly available. However, often only specific combinations of inhibitors are effective. Therefore, the prediction of potent combinatorial treatments is a major challenge in targeted cancer thera...
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Network quantification of EGFR signaling unveils potential for targeted combination therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_a4ed5dbe243d4ea28f53fa9649700665
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4ed5dbe243d4ea28f53fa9649700665
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.1038/msb.2013.29
