Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders
Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Clinical trials evaluating anti-CD20-mediated B-cell depletion in multiple sclerosis (MS) and neuromyelitis optica (NMO) generated encouraging results. Our recent studies in the MS model experimental autoimmune encephalomyelitis (EAE) attributed clinical benefit to extinction of activated B-cells, but cautioned that depletion of naïve B-cells may b...
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Full title
Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders
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TN_cdi_doaj_primary_oai_doaj_org_article_a53669eddd5d4ff7a992b53fe8eb94e0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a53669eddd5d4ff7a992b53fe8eb94e0
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/1742-2094-8-146
