Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implicatio...
Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. About 90% of ALS cases are without a known genetic cause. The human endogenous retrovirus multi-copy HERV-K(HML-2) group was recently reported to potentially contribute to neurodegeneration and disease pathogenesis in ALS because of transcriptional upregulation and toxic eff...
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Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins
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TN_cdi_doaj_primary_oai_doaj_org_article_a614b9b1c6a245569d81d26e1a7fc6ea
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a614b9b1c6a245569d81d26e1a7fc6ea
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-018-0275-3
