BTLA contributes to acute-on-chronic liver failure infection and mortality through CD4+ T-cell exhau...
BTLA contributes to acute-on-chronic liver failure infection and mortality through CD4+ T-cell exhaustion
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Author / Creator
Yu, Xueping , Yang, Feifei , Shen, Zhongliang , Zhang, Yao , Sun, Jian , Qiu, Chao , Zheng, Yijuan , Zhao, Weidong , Yuan, Songhua , Zeng, Dawu , Zhang, Shenyan , Long, Jianfei , Zhu, Mengqi , Zhang, Xueyun , Wu, Jingwen , Ma, Zhenxuan , Zhu, Haoxiang , Su, Milong , Xu, Jianqing , Li, Bin , Mao, Richeng , Su, Zhijun and Zhang, Jiming
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
B- and T-lymphocyte attenuator (BTLA) levels are increased in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF). This condition is characterized by susceptibility to infection and T-cell immune exhaustion. However, whether BTLA can induce T-cell immune exhaustion and increase the risk of infection remains unclear. He...
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BTLA contributes to acute-on-chronic liver failure infection and mortality through CD4+ T-cell exhaustion
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TN_cdi_doaj_primary_oai_doaj_org_article_a619c3b84cff48cc84735aeda44d8dce
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a619c3b84cff48cc84735aeda44d8dce
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-46047-8
