Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-...
Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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The extent to which changes in gene expression can influence cardiovascular disease risk across different tissue types has not yet been systematically explored. We have developed an analysis pipeline that integrates tissue-specific gene expression, Mendelian randomization and multiple-trait colocalization to develop functional mechanistic insight i...
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Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
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TN_cdi_doaj_primary_oai_doaj_org_article_a6a3acda54a84a81af4cdc6bf0621916
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6a3acda54a84a81af4cdc6bf0621916
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ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-019-0613-2