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Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-...

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6a3acda54a84a81af4cdc6bf0621916

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

About this item

Full title

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

Publisher

England: BioMed Central Ltd

Journal title

Genome medicine, 2019-01, Vol.11 (1), p.6-15, Article 6

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The extent to which changes in gene expression can influence cardiovascular disease risk across different tissue types has not yet been systematically explored. We have developed an analysis pipeline that integrates tissue-specific gene expression, Mendelian randomization and multiple-trait colocalization to develop functional mechanistic insight i...

Alternative Titles

Full title

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a6a3acda54a84a81af4cdc6bf0621916

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6a3acda54a84a81af4cdc6bf0621916

Other Identifiers

ISSN

1756-994X

E-ISSN

1756-994X

DOI

10.1186/s13073-019-0613-2

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