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ArticlesPeer ReviewedFull Text
DNA methylation aging clocks: challenges and recommendations
Author / Creator:Bell, Christopher G. ; Lowe, Robert ; Adams, Peter D. ; Baccarelli, Andrea A. ; Beck, Stephan ; Bell, Jordana T. ; Christensen, Brock C. ; Gladyshev, Vadim N. ; Heijmans, Bastiaan T. ; Horvath, Steve ; Ideker, Trey ; Issa, Jean-Pierre J. ; Kelsey, Karl T. ; Marioni, Riccardo E. ; Reik, Wolf ; Relton, Caroline L. ; Schalkwyk, Leonard C. ; Teschendorff, Andrew E. ; Wagner, Wolfgang ; Zhang, Kang ; Rakyan, Vardhman K.
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2019-11, Vol.20 (1), p.249-249, Article 249
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Epigenetic Epidemiology of Common Complex Disease: Prospects for Prediction, Prevention, and Treatment
Author / Creator:Relton, Caroline L. ; Davey Smith, George
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2010-10, Vol.7 (10), p.e1000356-e1000356
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Guidelines for performing Mendelian randomization investigations
Author / Creator:Burgess, Stephen ; Davey Smith, George ; Davies, Neil M. ; Dudbridge, Frank ; Gill, Dipender ; Glymour, M. Maria ; Hartwig, Fernando P. ; Holmes, Michael V. ; Minelli, Cosetta ; Relton, Caroline L. ; Theodoratou, Evropi
Publisher:London: Wellcome Trust Limited
Journal title:Wellcome open research, 2020-04, Vol.4, p.186
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Systematic identification of genetic influences on methylation across the human life course
Author / Creator:Gaunt, Tom R. ; Shihab, Hashem A. ; Hemani, Gibran ; Min, Josine L. ; Woodward, Geoff ; Lyttleton, Oliver ; Zheng, Jie ; Duggirala, Aparna ; McArdle, Wendy L. ; Ho, Karen ; Ring, Susan M. ; Evans, David M. ; Davey Smith, George ; Relton, Caroline L.
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2016-03, Vol.17 (1), p.61-61, Article 61
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Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study
Author / Creator:Nounu, Aayah ; Kar, Siddhartha P. ; Relton, Caroline L. ; Richmond, Rebecca C.
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2022-10, Vol.24 (1), p.66-66, Article 66
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Associations between high blood pressure and DNA methylation
Author / Creator:Kazmi, Nabila ; Elliott, Hannah R. ; Burrows, Kim ; Tillin, Therese ; Hughes, Alun D. ; Chaturvedi, Nish ; Gaunt, Tom R. ; Relton, Caroline L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-01, Vol.15 (1), p.e0227728
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A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome
Author / Creator:Richardson, Tom G. ; Hemani, Gibran ; Gaunt, Tom R. ; Relton, Caroline L. ; Davey Smith, George
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-01, Vol.11 (1), p.185-11, Article 185
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A comparison of the genes and genesets identified by GWAS and EWAS of fifteen complex traits
Author / Creator:Battram, Thomas ; Gaunt, Tom R. ; Relton, Caroline L. ; Timpson, Nicholas J. ; Hemani, Gibran
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-12, Vol.13 (1), p.7816-7816, Article 7816
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Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception
Author / Creator:Slieker, Roderick C. ; Relton, Caroline L. ; Gaunt, Tom R. ; Slagboom, P. Eline ; Heijmans, Bastiaan T.
Publisher:England: BioMed Central Ltd
Journal title:Epigenetics & chromatin, 2018-05, Vol.11 (1), p.25-25, Article 25
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Sex discordance in asthma and wheeze prevalence in two longitudinal cohorts
Author / Creator:Arathimos, Ryan ; Granell, Raquel ; Henderson, John ; Relton, Caroline L. ; Tilling, Kate
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-04, Vol.12 (4), p.e0176293-e0176293
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Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium
Author / Creator:Chen, Ling-Wei ; Aubert, Adrien M. ; Shivappa, Nitin ; Bernard, Jonathan Y. ; Mensink-Bout, Sara M. ; Geraghty, Aisling A. ; Mehegan, John ; Suderman, Matthew ; Polanska, Kinga ; Hanke, Wojciech ; Trafalska, Elzbieta ; Relton, Caroline L. ; Crozier, Sarah R. ; Harvey, Nicholas C. ; Cooper, Cyrus ; Duijts, Liesbeth ; Heude, Barbara ; Hébert, James R. ; McAuliffe, Fionnuala M. ; Kelleher, Cecily C. ; Phillips, Catherine M.
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2021-01, Vol.18 (1), p.e1003491
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Breastfeeding effects on DNA methylation in the offspring: A systematic literature review
Author / Creator:Hartwig, Fernando Pires ; Loret de Mola, Christian ; Davies, Neil Martin ; Victora, Cesar Gomes ; Relton, Caroline L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-03, Vol.12 (3), p.e0173070-e0173070
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Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study
Author / Creator:Morales Berstein, Fernanda ; McCartney, Daniel L ; Lu, Ake T ; Tsilidis, Konstantinos K ; Bouras, Emmanouil ; Haycock, Philip ; Burrows, Kimberley ; Phipps, Amanda I ; Buchanan, Daniel D ; Cheng, Iona ; Martin, Richard M ; Davey Smith, George ; Relton, Caroline L ; Horvath, Steve ; Marioni, Riccardo E ; Richardson, Tom G ; Richmond, Rebecca C
Publisher:England: eLife Sciences Publications, Ltd
Journal title:eLife, 2022-03, Vol.11
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Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis
Author / Creator:Yarmolinsky, James ; Relton, Caroline L. ; Lophatananon, Artitaya ; Muir, Kenneth ; Menon, Usha ; Gentry-Maharaj, Aleksandra ; Walther, Axel ; Zheng, Jie ; Fasching, Peter ; Zheng, Wei ; Yin Ling, Woo ; Park, Sue K. ; Kim, Byoung-Gie ; Choi, Ji-Yeob ; Park, Boyoung ; Davey Smith, George ; Martin, Richard M. ; Lewis, Sarah J.
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2019-08, Vol.16 (8), p.e1002893
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DNA Methylation Patterns in Cord Blood DNA and Body Size in Childhood
Author / Creator:Relton, Caroline L. ; Groom, Alexandra ; St. Pourcain, Beate ; Sayers, Adrian E. ; Swan, Daniel C. ; Embleton, Nicholas D. ; Pearce, Mark S. ; Ring, Susan M. ; Northstone, Kate ; Tobias, Jon H. ; Trakalo, Joseph ; Ness, Andy R. ; Shaheen, Seif O. ; Davey Smith, George
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-03, Vol.7 (3), p.e31821-e31821
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Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET consortium
Author / Creator:Chen, Ling-Wei ; Aubert, Adrien M. ; Shivappa, Nitin ; Bernard, Jonathan Y. ; Mensink-Bout, Sara M. ; Geraghty, Aisling A. ; Mehegan, John ; Suderman, Matthew ; Polanska, Kinga ; Hanke, Wojciech ; Jankowska, Agnieszka ; Relton, Caroline L. ; Crozier, Sarah R. ; Harvey, Nicholas C. ; Cooper, Cyrus ; Hanson, Mark ; Godfrey, Keith M. ; Gaillard, Romy ; Duijts, Liesbeth ; Heude, Barbara ; Hébert, James R. ; McAuliffe, Fionnuala M. ; Kelleher, Cecily C. ; Phillips, Catherine M.
Publisher:England: BioMed Central Ltd
Journal title:BMC medicine, 2021-02, Vol.19 (1), p.33-14, Article 33
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Differences in smoking associated DNA methylation patterns in South Asians and Europeans
Author / Creator:Elliott, Hannah R ; Tillin, Therese ; McArdle, Wendy L ; Ho, Karen ; Duggirala, Aparna ; Frayling, Tim M ; Davey Smith, George ; Hughes, Alun D ; Chaturvedi, Nish ; Relton, Caroline L
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2014-02, Vol.6 (1), p.4-4, Article 4
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Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
Author / Creator:Taylor, Kurt ; Davey Smith, George ; Relton, Caroline L. ; Gaunt, Tom R. ; Richardson, Tom G.
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2019-01, Vol.11 (1), p.6-15, Article 6
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Distinct DNA methylation profiles in subtypes of orofacial cleft
Author / Creator:Sharp, Gemma C. ; Ho, Karen ; Davies, Amy ; Stergiakouli, Evie ; Humphries, Kerry ; McArdle, Wendy ; Sandy, Jonathan ; Davey Smith, George ; Lewis, Sarah J. ; Relton, Caroline L.
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2017-06, Vol.9 (1), p.63-63, Article 63
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Characterization of whole-genome autosomal differences of DNA methylation between men and women
Author / Creator:Singmann, Paula ; Shem-Tov, Doron ; Wahl, Simone ; Grallert, Harald ; Fiorito, Giovanni ; Shin, So-Youn ; Schramm, Katharina ; Wolf, Petra ; Kunze, Sonja ; Baran, Yael ; Guarrera, Simonetta ; Vineis, Paolo ; Krogh, Vittorio ; Panico, Salvatore ; Tumino, Rosario ; Kretschmer, Anja ; Gieger, Christian ; Peters, Annette ; Prokisch, Holger ; Relton, Caroline L. ; Matullo, Giuseppe ; Illig, Thomas ; Waldenberger, Melanie ; Halperin, Eran
Publisher:England: BioMed Central Ltd
Journal title:Epigenetics & chromatin, 2015-10, Vol.8 (1), p.43, Article 43
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DNA methylation aging clocks: challenges and recommendations

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Epigenetic Epidemiology of Common Complex Disease: Prospects for Prediction, Prevention, and Treatment

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Guidelines for performing Mendelian randomization investigations

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Systematic identification of genetic influences on methylation across the human life course

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Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study

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Associations between high blood pressure and DNA methylation

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A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

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A comparison of the genes and genesets identified by GWAS and EWAS of fifteen complex traits

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Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception

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Sex discordance in asthma and wheeze prevalence in two longitudinal cohorts

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Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium

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Breastfeeding effects on DNA methylation in the offspring: A systematic literature review

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Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

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Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis

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DNA Methylation Patterns in Cord Blood DNA and Body Size in Childhood

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Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET consortium

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Differences in smoking associated DNA methylation patterns in South Asians and Europeans

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Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

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Distinct DNA methylation profiles in subtypes of orofacial cleft

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Characterization of whole-genome autosomal differences of DNA methylation between men and women

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