Effects of cryo-EM cooling on structural ensembles
Effects of cryo-EM cooling on structural ensembles
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Structure determination by cryo electron microscopy (cryo-EM) provides information on structural heterogeneity and ensembles at atomic resolution. To obtain cryo-EM images of macromolecules, the samples are first rapidly cooled down to cryogenic temperatures. To what extent the structural ensemble is perturbed during cooling is currently unknown. H...
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Effects of cryo-EM cooling on structural ensembles
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TN_cdi_doaj_primary_oai_doaj_org_article_a6b6b8b56ca94c4685df80659654c19f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6b6b8b56ca94c4685df80659654c19f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29332-2