Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediat...
Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages
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Author / Creator
He, Xiu , Chen, Shi , Li, Chao , Ban, Jiaqi , Wei, Yungeng , He, Yangyang , Liu, Fangwei , Chen, Ying and Chen, Jie
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Silicosis is an occupational lung disease characterized by persistent inflammation and irreversible fibrosis. Crystalline silica (CS) particles are mainly phagocytized by alveolar macrophages (AMs), which trigger apoptosis, inflammation, and pulmonary fibrosis. Previously, we found that autophagy-lysosomal system dysfunction in AMs was involved in...
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Full title
Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages
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TN_cdi_doaj_primary_oai_doaj_org_article_a7b7fe7d841d46dd927933f3fd463fbb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7b7fe7d841d46dd927933f3fd463fbb
Other Identifiers
ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells9010122
