Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK...
Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Previous studies have shown a major green tea polyphenol (-)-epigallocatechin-3-gallate ((-)-EGCG) as a powerful anti-cancer agent. However, its poor bioavailability and requirement of a high dosage to manifest activity have restricted its clinical application. Recently, our team synthesized a peracetate-protected derivative of EGCG, which can act...
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Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_a7f334cec11049b0b24c5bf84175489e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7f334cec11049b0b24c5bf84175489e
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1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-020-07455-3