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Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a8051c0c20ff4387a3e2b378823c5cf6

Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

About this item

Full title

Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

Publisher

Basel: MDPI AG

Journal title

Biomolecules (Basel, Switzerland), 2021-05, Vol.11 (6), p.800

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

Macrophage plasticity enables cells to obtain different functions over a broad proinflammatory and repairing spectrum. In different conditions, macrophages can be induced by high-mobility group box 1 (HMGB1), a nuclear DNA-binding protein that activates innate immunity, to polarize towards a pro- (M1) or anti-inflammatory (M2) phenotype. In this st...

Alternative Titles

Full title

Disulfide and Fully Reduced HMGB1 Induce Different Macrophage Polarization and Migration Patterns

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a8051c0c20ff4387a3e2b378823c5cf6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a8051c0c20ff4387a3e2b378823c5cf6

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom11060800

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