Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The asymmetric cross-coupling reaction is developed as a straightforward strategy toward 1,1-diaryl alkanes, which are a key skeleton in a series of natural products and bioactive molecules in recent years. Here we report an enantioselective benzylic C(sp
3
)−H bond arylation via photoredox/nickel dual catalysis. Sterically hindered chiral bi...
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Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis
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TN_cdi_doaj_primary_oai_doaj_org_article_a82023b06903447ca014df5aca9328b6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a82023b06903447ca014df5aca9328b6
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11392-6