ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progen...
ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progenitor cell function
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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CCCTC binding factor (CTCF) is an important factor in the maintenance of chromatin–chromatin interactions, yet the mechanism regulating its binding to chromatin is unknown. We demonstrate that zinc finger protein 143 (ZNF143) is a key regulator for CTCF-bound promoter–enhancer loops. In the murine genome, a large percentage of CTCF and ZNF143 DNA b...
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ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progenitor cell function
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TN_cdi_doaj_primary_oai_doaj_org_article_a828711a0de141af954d80bfa7285356
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a828711a0de141af954d80bfa7285356
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20282-1
