Structure-based characterization of novel TRPV5 inhibitors
Structure-based characterization of novel TRPV5 inhibitors
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England: eLife Science Publications, Ltd
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Language
English
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England: eLife Science Publications, Ltd
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Transient receptor potential vanilloid 5 (TRPV5) is a highly calcium selective ion channel that acts as the rate-limiting step of calcium reabsorption in the kidney. The lack of potent, specific modulators of TRPV5 has limited the ability to probe the contribution of TRPV5 in disease phenotypes such as hypercalcemia and nephrolithiasis. Here, we pe...
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Structure-based characterization of novel TRPV5 inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_a82f5f6720e94648810a1aa64e4d1450
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a82f5f6720e94648810a1aa64e4d1450
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.49572
