Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis
Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Systemic AL amyloidosis is one of the most frequently diagnosed forms of systemic amyloidosis. It arises from mutational changes in immunoglobulin light chains. To explore whether these mutations may affect the structure of the formed fibrils, we determine and compare the fibril structures from several patients with cardiac AL amyloidosis. All pati...
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Full title
Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis
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TN_cdi_doaj_primary_oai_doaj_org_article_a8a7533f549f4f7b811b7eb83658803c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a8a7533f549f4f7b811b7eb83658803c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-49520-6
