Log in to save to my catalogue

Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a967244e4d8746a2a75d6f0db2491acc

Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

About this item

Full title

Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2022-02, Vol.11

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Interactions of developing T cells with Aire
medullary thymic epithelial cells expressing high levels of MHCII molecules (mTEC
) are critical for the induction of central tolerance in the thymus. In turn, thymocytes regulate the cellularity of Aire
mTEC
. However, it remains unknown whether thymocytes control the precursors of Aire
m...

Alternative Titles

Full title

Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a967244e4d8746a2a75d6f0db2491acc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a967244e4d8746a2a75d6f0db2491acc

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.69982

How to access this item