Cancer exosomes induce tumor innervation
Cancer exosomes induce tumor innervation
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Author / Creator
Madeo, Marianna , Colbert, Paul L. , Vermeer, Daniel W. , Lucido, Christopher T. , Cain, Jacob T. , Vichaya, Elisabeth G. , Grossberg, Aaron J. , Muirhead, DesiRae , Rickel, Alex P. , Hong, Zhongkui , Zhao, Jing , Weimer, Jill M. , Spanos, William C. , Lee, John H. , Dantzer, Robert and Vermeer, Paola D.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Patients with densely innervated tumors suffer with increased metastasis and decreased survival as compared to those with less innervated tumors. We hypothesize that in some tumors, nerves are acquired by a tumor-induced process, called axonogenesis. Here, we use PC12 cells as an in vitro neuronal model, human tumor samples and murine in vivo model...
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Full title
Cancer exosomes induce tumor innervation
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TN_cdi_doaj_primary_oai_doaj_org_article_aaa8e375f8d44392b380867c6849d0bc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aaa8e375f8d44392b380867c6849d0bc
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06640-0