Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinom...
Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progression
About this item
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Author / Creator
Wang, Haichuan , Wang, Pan , Xu, Meng , Song, Xinhua , Wu, Hong , Evert, Matthias , Calvisi, Diego F. , Zeng, Yong and Chen, Xin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Dysregulation of transforming growth factor-beta (TGFβ) signaling has been implicated in liver carcinogenesis with both tumor promoting and inhibiting activities. Activation of the c-MYC protooncogene is another critical genetic event in hepatocellular carcinoma (HCC). However, the precise functional crosstalk between c-MYC and TGFβ signaling pathw...
Alternative Titles
Full title
Distinct functions of transforming growth factor-β signaling in c-MYC driven hepatocellular carcinoma initiation and progression
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_abe6dba9aa36446c801ce9127474ec64
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_abe6dba9aa36446c801ce9127474ec64
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-03488-z
