Heat shock factor 1 inhibits the mitochondrial apoptosis pathway by regulating second mitochondria-d...
Heat shock factor 1 inhibits the mitochondrial apoptosis pathway by regulating second mitochondria-derived activator of caspase to promote pancreatic tumorigenesis
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Author / Creator
Liang, Wenjin , Liao, Yong , Zhang, Jing , Huang, Qi , Luo, Wei , Yu, Jidong , Gong, Jianhua , Zhou, Yi , Li, Xuan , Tang, Bo , He, Songqing and Yang, Jinghong
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
As a relatively conservative transcriptional regulator in biological evolution, heat shock factor 1 (HSF1) is activated by, and regulates the expression of heat shock proteins (HSPs) in response to a variety of stress conditions. HSF1 also plays a key role in regulating the development of various tumors; however, its role in pancreatic cancer and t...
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Full title
Heat shock factor 1 inhibits the mitochondrial apoptosis pathway by regulating second mitochondria-derived activator of caspase to promote pancreatic tumorigenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_abf510587eca4cf2a4652fad6524b5cd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_abf510587eca4cf2a4652fad6524b5cd
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-017-0537-x