Bulk tissue cell type deconvolution with multi-subject single-cell expression reference
Bulk tissue cell type deconvolution with multi-subject single-cell expression reference
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Knowledge of cell type composition in disease relevant tissues is an important step towards the identification of cellular targets of disease. We present MuSiC, a method that utilizes cell-type specific gene expression from single-cell RNA sequencing (RNA-seq) data to characterize cell type compositions from bulk RNA-seq data in complex tissues. By...
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Full title
Bulk tissue cell type deconvolution with multi-subject single-cell expression reference
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TN_cdi_doaj_primary_oai_doaj_org_article_ac842de2714346f8a022547ffa6e51ad
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ac842de2714346f8a022547ffa6e51ad
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-08023-x
