β-Catenin signaling in hepatocellular carcinoma
β-Catenin signaling in hepatocellular carcinoma
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Author / Creator
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Deregulated Wnt/β-catenin signaling is one of the main genetic alterations in human hepatocellular carcinoma (HCC). Comprehensive genomic analyses have revealed that gain-of-function mutation of CTNNB1, which encodes β-catenin, and loss-of-function mutation of AXIN1 occur in approximately 35% of human HCC samples. Human HCCs with activation of the...
Alternative Titles
Full title
β-Catenin signaling in hepatocellular carcinoma
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ac9a697243b64e79b57cc27e96df1568
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ac9a697243b64e79b57cc27e96df1568
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI154515
