Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and...
Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy
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Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Neuronopathic Gaucher disease (nGD) is a rare neurodegenerative disorder caused by biallelic mutations in
and buildup of glycosphingolipids in lysosomes. Neuronal injury and cell death are prominent pathological features; however, the role of
in individual cell types and involvement of microglia, blood-derived macrophages, and immune infiltra...
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Full title
Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_ae7987b768304a36b201d016d7515a85
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ae7987b768304a36b201d016d7515a85
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.79830
