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FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation

FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aeb39fb62c694bcdbd5abbf89127b373

FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation

About this item

Full title

FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation

Publisher

England: BioMed Central Ltd

Journal title

BMC musculoskeletal disorders, 2024-04, Vol.25 (1), p.282-282, Article 282

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Ferritin heavy chain 1 (FTH1) is an important subunit of ferro-storing proteins and is indispensable for iron metabolism. Though it has been extensively studied in numerous organs and diseases, the relationship between FTH1 and osteoarthritis (OA) is unclear.
Primary murine chondrocytes and cartilage explants were treated with FTH1 siRNA for 72...

Alternative Titles

Full title

FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_aeb39fb62c694bcdbd5abbf89127b373

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aeb39fb62c694bcdbd5abbf89127b373

Other Identifiers

ISSN

1471-2474

E-ISSN

1471-2474

DOI

10.1186/s12891-024-07411-3

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