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ArticlesPeer ReviewedFull Text
AB0171 Aggrecan Degradation Is Not Just Aggrecan Degradation – A Study of Neo-Epitopes (NITEGE and ARGS) of Aggrecanase Degradation
Author / Creator:Siebuhr, A.S. ; He, Y. ; Hoielt, S. ; Luo, Y.R. ; Karsdal, M.A. ; Bay-Jensen, A.-C.
Publisher:Kidlington: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2016-06, Vol.75 (Suppl 2), p.955
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Clinical characterization of patients with autosomal dominant short stature due to aggrecan mutations
Author / Creator:Gkourogianni, Alexandra ; Andrew, Melissa ; Tyzinski, Leah ; Crocker, Melissa ; Douglas, Jessica ; Dunbar, Nancy ; Fairchild, Jan ; Funari, Mariana F. A ; Heath, Karen E ; Jorge, Alexander A.L ; Kurtzman, Tracey ; LaFranchi, Stephen ; Lalani, Seema ; Lebl, Jan ; Lin, Yuezhen ; Los, Evan ; Newbern, Dorothee ; Nowak, Catherine ; Olson, Micah ; Popovic, Jadranka ; Průhová, Štěpánka ; Elblova, Lenka ; Quintos, Jose Bernardo ; Segerlund, Emma ; Sentchordi, Lucia ; Shinawi, Marwan ; Stattin, Eva-Lena ; Swartz, Jonathan ; Ariadna, González-del Angel ; Sinhué, Díaz-Cuéllar ; Hosono, Hidekazu ; Sanchez-Lara, Pedro A ; Hwa, Vivian ; Baron, Jeffrey ; Nilsson, Ola ; Dauber, Andrew
Publisher:Washington, DC: Endocrine Society
Journal title:The journal of clinical endocrinology and metabolism, 2017-02, Vol.102 (2), p.460-469
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ArticlesPeer ReviewedFull Text
Aggrecan: a new biomarker for acute type A aortic dissection
Author / Creator:König, Karl C. ; Lahm, Harald ; Dreßen, Martina ; Doppler, Stefanie A. ; Eichhorn, Stefan ; Beck, Nicole ; Kraehschuetz, Kathrin ; Doll, Sophia ; Holdenrieder, Stefan ; Kastrati, Adnan ; Lange, Rüdiger ; Krane, Markus
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-05, Vol.11 (1), p.10371-10371, Article 10371
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Reference EntriesFull Text
aggrecan
Publisher:Oxford University Press
Journal title:A Dictionary of Biomedicine, 2019
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ArticlesPeer ReviewedFull Text
Structure and function of aggrecan
Author / Creator:KIANI, Chris ; CHEN, Liwen ; WU, Yao Jiong ; YEE, Albert J ; YANG, Burton B
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2002-03, Vol.12 (1), p.19-32
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ArticlesPeer ReviewedFull Text
Aggrecan is required for chondrocyte differentiation in ATDC5 chondroprogenitor cells
Author / Creator:Hodax, Juanita K ; Quintos, Jose Bernardo ; Gruppuso, Philip A ; Chen, Qian ; Desai, Salomi ; Jayasuriya, Chathuraka T
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-06, Vol.14 (6), p.e0218399-e0218399
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ArticlesPeer ReviewedFull Text
The role of aggrecan in normal and osteoarthritic cartilage
Author / Creator:Roughley, Peter J ; Mort, John S
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of experimental orthopaedics, 2014-12, Vol.1 (1), p.8-11, Article 8
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ArticlesPeer ReviewedFull Text
Aggrecan, the Primary Weight-Bearing Cartilage Proteoglycan, Has Context-Dependent, Cell-Directive Properties in Embryonic Development and Neurogenesis: Aggrecan Glycan Side Chain Modifications Convey...
Author / Creator:Hayes, Anthony J ; Melrose, James
Publisher:Switzerland: MDPI
Journal title:Biomolecules (Basel, Switzerland), 2020-08, Vol.10 (9), p.1244
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ArticlesPeer ReviewedFull Text
A plastic aggrecan barrier modulated by peripheral energy state gates metabolic signal access to arcuate neurons
Author / Creator:Kuczynski-Noyau, Laura ; Karmann, Sixtine ; Alberton, Paolo ; Martinez-Corral, Ines ; Nampoothiri, Sreekala ; Sauvé, Florent ; Lhomme, Tori ; Quarta, Carmelo ; Apte, Suneel S. ; Bouret, Sébastien ; Aszodi, Attila ; Rasika, Sowmyalakshmi ; Ciofi, Philippe ; Dam, Julie ; Prévot, Vincent ; Mattot, Virginie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-08, Vol.15 (1), p.6701-11, Article 6701
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ArticlesPeer ReviewedFull Text
Treatment of Short Stature in Aggrecan-deficient Patients With Recombinant Human Growth Hormone: 1-Year Response
Author / Creator:Muthuvel, Gajanthan ; Dauber, Andrew ; Alexandrou, Eirene ; Tyzinski, Leah ; Andrew, Melissa ; Hwa, Vivian ; Backeljauw, Philippe
Publisher:US: Oxford University Press
Journal title:The journal of clinical endocrinology and metabolism, 2022-05, Vol.107 (5), p.e2103-e2109
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ArticlesPeer ReviewedFull Text
NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker
Author / Creator:Perret, Raul ; Escuriol, Julien ; Velasco, Valérie ; Mayeur, Laetitia ; Soubeyran, Isabelle ; Delfour, Christophe ; Aubert, Sébastien ; Polivka, Marc ; Karanian, Marie ; Meurgey, Alexandra ; Le Guellec, Sophie ; Weingertner, Noelle ; Hoeller, Sylvia ; Coindre, Jean-Michel ; Larousserie, Frédérique ; Pierron, Gaëlle ; Tirode, Franck ; Le Loarer, François
Publisher:New York: Nature Publishing Group US
Journal title:Modern pathology, 2020-10, Vol.33 (10), p.1930-1944
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ArticlesPeer ReviewedFull Text
Dysregulated MiR-3150a-3p Promotes Lumbar Intervertebral Disc Degeneration by Targeting Aggrecan
Author / Creator:Zhang, Bin ; Guo, Wei ; Sun, Chao ; Duan, Hui-Quan ; Yu, Bing-Bing ; Mu, Kun ; Guan, Yue-Yan ; Li, Yan ; Liu, Shen ; Liu, Yang ; Ban, De-Xiang ; Ruan, Wen-Dong ; Kong, Xiao-Hong ; Xing, Cong ; Ning, Guang-Zhi ; Feng, Shi-Qing
Publisher:Basel, Switzerland: S. Karger AG
Journal title:Cellular physiology and biochemistry, 2018-04, Vol.45 (6), p.2506-2515
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ArticlesPeer ReviewedFull Text
Injectable stress relaxation gelatin-based hydrogels with positive surface charge for adsorption of aggrecan and facile cartilage tissue regeneration
Author / Creator:Wang, Kai-Yang ; Jin, Xiang-Yun ; Ma, Yu-Hui ; Cai, Wei-Jie ; Xiao, Wei-Yuan ; Li, Zhi-Wei ; Qi, Xin ; Ding, Jian
Publisher:England: BioMed Central Ltd
Journal title:Journal of nanobiotechnology, 2021-07, Vol.19 (1), p.214-214, Article 214
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ArticlesPeer ReviewedFull Text
POS0104 A PHASE 2B DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMIZED CLINICAL TRIAL OF SB-061, AN AGGRECAN MIMETIC, IN SUBJECTS WITH SYMPTOMATIC KNEE OSTEOARTHRITIS
Author / Creator:Bihlet, A.R. ; Byrjalsen, I. ; Mundbjerg, K. ; Alexandersen, P. ; Rovsing, H. ; Axelsen, T. ; Andersen, J.R. ; Metnik, A. ; Bachtell, N. ; Brett, A. ; Christiansen, C.
Publisher:Kidlington: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2023-06, Vol.82 (Suppl 1), p.265-266
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ArticlesPeer ReviewedFull Text
A plastic aggrecan barrier modulated by peripheral energy state gates metabolic signal access to arcuate neurons
Author / Creator:Kuczynski-Noyau, Laura ; Karmann, Sixtine ; Alberton, Paolo ; Martinez-Corral, Ines ; Nampoothiri, Sreekala ; Sauvé, Florent ; Lhomme, Tori ; Quarta, Carmelo ; Apte, Suneel ; Bouret, Sébastien ; Aszodi, Attila ; Rasika, Sowmyalakshmi ; Ciofi, Philippe ; Dam, Julie ; Prévot, Vincent ; Mattot, Virginie
Publisher:Nature Publishing Group
Journal title:Nature communications, 2024-08, Vol.15 (1)
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ArticlesPeer ReviewedFull Text
Catabolic mediators from TLR2-mediated proteoglycan aggrecan peptide-stimulated chondrocytes are reduced by Lactobacillus-conditioned media
Author / Creator:Sengprasert, Panjana ; Waitayangkoon, Palapun ; Kamenkit, Ousakorn ; Sawatpanich, Ajcharaporn ; Chaichana, Thiamjit ; Wongphoom, Jutamas ; Ngarmukos, Srihatach ; Taweevisit, Mana ; Lotinun, Sutada ; Tumwasorn, Somying ; Tanavalee, Aree ; Reantragoon, Rangsima
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-08, Vol.14 (1), p.18043-15, Article 18043
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ArticlesPeer ReviewedFull Text
Aggrecan, aging and assembly in articular cartilage
Author / Creator:Dudhia, J
Publisher:Switzerland: Springer Nature B.V
Journal title:Cellular and molecular life sciences : CMLS, 2005-10, Vol.62 (19-20), p.2241-2256
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ArticlesPeer ReviewedFull Text
The minor collagens in articular cartilage
Author / Creator:Luo, Yunyun ; Sinkeviciute, Dovile ; He, Yi ; Karsdal, Morten ; Henrotin, Yves ; Mobasheri, Ali ; Önnerfjord, Patrik ; Bay-Jensen, Anne
Publisher:Beijing: Higher Education Press
Journal title:Protein & cell, 2017-08, Vol.8 (8), p.560-572
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ArticlesPeer ReviewedFull Text
An Anterior Cruciate Ligament Rupture Increases Levels of Urine N-terminal Cross-linked Telopeptide of Type I Collagen, Urine C-terminal Cross-linked Telopeptide of Type II Collagen, Serum Aggrecan AR...
Author / Creator:Hagemans, Frans J.A. ; Larsson, Staffan ; Reijman, Max ; Frobell, Richard B. ; Struglics, Andre ; Meuffels, Duncan E.
Publisher:Los Angeles, CA: SAGE Publications
Journal title:The American journal of sports medicine, 2021-11, Vol.49 (13), p.3534-3543
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ArticlesPeer ReviewedFull Text
Tenascin-R promotes assembly of the extracellular matrix of perineuronal nets via clustering of aggrecan
Author / Creator:Morawski, Markus ; Dityatev, Alexander ; Hartlage-Rübsamen, Maike ; Blosa, Maren ; Holzer, Max ; Flach, Katharina ; Pavlica, Sanja ; Dityateva, Galina ; Grosche, Jens ; Brückner, Gert ; Schachner, Melitta
Publisher:England: The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2014-10, Vol.369 (1654), p.20140046-20140046
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AB0171 Aggrecan Degradation Is Not Just Aggrecan Degradation – A Study of Neo-Epitopes (NITEGE and ARGS) of Aggrecanase Degradation

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Clinical characterization of patients with autosomal dominant short stature due to aggrecan mutations

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Aggrecan: a new biomarker for acute type A aortic dissection

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aggrecan

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Structure and function of aggrecan

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Aggrecan is required for chondrocyte differentiation in ATDC5 chondroprogenitor cells

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The role of aggrecan in normal and osteoarthritic cartilage

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Aggrecan, the Primary Weight-Bearing Cartilage Proteoglycan, Has Context-Dependent, Cell-Directive Properties in Embryonic Development and Neurogenesis: Aggrecan Glycan Side Chain Modifications Convey...

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A plastic aggrecan barrier modulated by peripheral energy state gates metabolic signal access to arcuate neurons

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Treatment of Short Stature in Aggrecan-deficient Patients With Recombinant Human Growth Hormone: 1-Year Response

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NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker

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Dysregulated MiR-3150a-3p Promotes Lumbar Intervertebral Disc Degeneration by Targeting Aggrecan

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Injectable stress relaxation gelatin-based hydrogels with positive surface charge for adsorption of aggrecan and facile cartilage tissue regeneration

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POS0104 A PHASE 2B DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMIZED CLINICAL TRIAL OF SB-061, AN AGGRECAN MIMETIC, IN SUBJECTS WITH SYMPTOMATIC KNEE OSTEOARTHRITIS

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A plastic aggrecan barrier modulated by peripheral energy state gates metabolic signal access to arcuate neurons

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Catabolic mediators from TLR2-mediated proteoglycan aggrecan peptide-stimulated chondrocytes are reduced by Lactobacillus-conditioned media

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Aggrecan, aging and assembly in articular cartilage

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The minor collagens in articular cartilage

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An Anterior Cruciate Ligament Rupture Increases Levels of Urine N-terminal Cross-linked Telopeptide of Type I Collagen, Urine C-terminal Cross-linked Telopeptide of Type II Collagen, Serum Aggrecan AR...

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Tenascin-R promotes assembly of the extracellular matrix of perineuronal nets via clustering of aggrecan

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