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Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following...

Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aede84a0c7d6439186581631dae32ce9

Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult

About this item

Full title

Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2017-04, Vol.6

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

The PKR-like endoplasmic reticulum kinase (PERK) arm of the Integrated Stress Response (ISR) is implicated in neurodegenerative disease, although the regulators and consequences of PERK activation following neuronal injury are poorly understood. Here we show that PERK signaling is a component of the mouse MAP kinase neuronal stress response control...

Alternative Titles

Full title

Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_aede84a0c7d6439186581631dae32ce9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aede84a0c7d6439186581631dae32ce9

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.20725

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