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Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis

Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af32fe3ff392445c91651d974582a84f

Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis

About this item

Full title

Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis

Publisher

England: BioMed Central Ltd

Journal title

Arthritis research & therapy, 2023-09, Vol.25 (1), p.176-15, Article 176

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Synovial fibroblasts in rheumatoid arthritis (RAFLS) exhibit a pathological aberration of glycolysis and glutaminolysis. Henceforth, we aimed to investigate if dual inhibition of these pathways by phytobiological compound c28MS has the potential of synergistic therapy for arthritis by targeting both glucose and glutamine metabolism.
The presence...

Alternative Titles

Full title

Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_af32fe3ff392445c91651d974582a84f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af32fe3ff392445c91651d974582a84f

Other Identifiers

ISSN

1478-6362,1478-6354

E-ISSN

1478-6362

DOI

10.1186/s13075-023-03161-0

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