Role of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondria...
Role of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondrial ROS generation and TGF-β1 activity
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant lung remodeling and the excessive accumulation of extracellular matrix (ECM) proteins. In a previous study, we found that the levels of ornithine aminotransferase (OAT), a principal enzyme in the proline metabolism pathway, were increased in the lungs of patients with IPF. However, th...
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Role of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondrial ROS generation and TGF-β1 activity
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TN_cdi_doaj_primary_oai_doaj_org_article_af5e4a708dc342ef9ec9cdffe61294e4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af5e4a708dc342ef9ec9cdffe61294e4
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ISSN
2092-6413,1226-3613
E-ISSN
2092-6413
DOI
10.1038/s12276-024-01170-w
