Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, p...
Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We have previously shown that glioblastoma stem cells (GSCs) are enriched in the hypoxic tumor microenvironment, and that monocarboxylate transporter-4 (MCT4) is critical for mediating GSC signaling in hypoxia. Basigin is involved in many physiological functions during early stages of development and in cancer and is required for functional plasma...
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Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression
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TN_cdi_doaj_primary_oai_doaj_org_article_af63e06427b245939b37411cb3ee906c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af63e06427b245939b37411cb3ee906c
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-04612-w
