Detrimental role of sphingosine kinase 1 in kidney damage in DOCA-salt hypertensive model: evidence...
Detrimental role of sphingosine kinase 1 in kidney damage in DOCA-salt hypertensive model: evidence from knockout mice
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Publisher
England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Sphingosine-1-phosphate (S1P) is a bioactive metabolite of sphingolipids and produced by sphingosine kinases (SphK1 and SphK2). SphK1/S1P pathway is implicated in the progression of chronic kidney disease. However, the role of SphK1/S1P pathway in renal injury in hypertension has not been reported. This study tested the hypothesis that SphK1/S1P pa...
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Full title
Detrimental role of sphingosine kinase 1 in kidney damage in DOCA-salt hypertensive model: evidence from knockout mice
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TN_cdi_doaj_primary_oai_doaj_org_article_afefc3974f2b46c6ba4e0106c052cf97
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_afefc3974f2b46c6ba4e0106c052cf97
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ISSN
1471-2369
E-ISSN
1471-2369
DOI
10.1186/s12882-020-01815-8
