Algorithm-aided engineering of aliphatic halogenase WelO5 for the asymmetric late-stage functionaliz...
Algorithm-aided engineering of aliphatic halogenase WelO5 for the asymmetric late-stage functionalization of soraphens
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Late-stage functionalization of natural products offers an elegant route to create novel entities in a relevant biological target space. In this context, enzymes capable of halogenating sp
3
carbons with high stereo- and regiocontrol under benign conditions have attracted particular attention. Enabled by a combination of smart library design...
Alternative Titles
Full title
Algorithm-aided engineering of aliphatic halogenase WelO5 for the asymmetric late-stage functionalization of soraphens
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b0080e192c1f4807837af8d63df4a6df
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b0080e192c1f4807837af8d63df4a6df
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-27999-1
