Specification of haematopoietic stem cell fate via modulation of mitochondrial activity
Specification of haematopoietic stem cell fate via modulation of mitochondrial activity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Haematopoietic stem cells (HSCs) differ from their committed progeny by relying primarily on anaerobic glycolysis rather than mitochondrial oxidative phosphorylation for energy production. However, whether this change in the metabolic program is the cause or the consequence of the unique function of HSCs remains unknown. Here we show that enforced...
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Full title
Specification of haematopoietic stem cell fate via modulation of mitochondrial activity
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TN_cdi_doaj_primary_oai_doaj_org_article_b081f3f436004a1183c52fe48a38b2c1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b081f3f436004a1183c52fe48a38b2c1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms13125
