Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by...
Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution
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Switzerland: MDPI AG
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English
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Publisher
Switzerland: MDPI AG
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Archaeal DNA polymerases from the B-family (polB) have found essential applications in biotechnology. In addition, some of their variants can accept a wide range of modified nucleotides or xenobiotic nucleotides, such as 1,5-anhydrohexitol nucleic acid (HNA), which has the unique ability to selectively cross-pair with DNA and RNA. This capacity is...
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Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution
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TN_cdi_doaj_primary_oai_doaj_org_article_b095ac31ee974895994ea5dcc61f0c3a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b095ac31ee974895994ea5dcc61f0c3a
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom10121647
