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ArticlesPeer ReviewedFull Text
Synthetic Genetic Polymers Capable of Heredity and Evolution
Author / Creator:Pinheiro, Vitor B. ; Taylor, Alexander I. ; Cozens, Christopher ; Abramov, Mikhail ; Renders, Marleen ; Zhang, Su ; Chaput, John C. ; Wengel, Jesper ; Peak-Chew, Sew-Yeu ; McLaughlin, Stephen H. ; Herdewijn, Piet ; Holliger, Philipp
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2012-04, Vol.336 (6079), p.341-344
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Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects
Author / Creator:Bekerman, Elena ; Neveu, Gregory ; Shulla, Ana ; Brannan, Jennifer ; Pu, Szu-Yuan ; Wang, Stanley ; Xiao, Fei ; Barouch-Bentov, Rina ; Bakken, Russell R. ; Mateo, Roberto ; Govero, Jennifer ; Nagamine, Claude M. ; Diamond, Michael S. ; De Jonghe, Steven ; Herdewijn, Piet ; Dye, John M. ; Randall, Glenn ; Einav, Shirit
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-04, Vol.127 (4), p.1338-1352
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A two-residue nascent-strand steric gate controls synthesis of 2′-O-methyl- and 2′-O-(2-methoxyethyl)-RNA
Author / Creator:Freund, Niklas ; Taylor, Alexander I. ; Arangundy-Franklin, Sebastian ; Subramanian, Nithya ; Peak-Chew, Sew-Yeu ; Whitaker, Amy M. ; Freudenthal, Bret D. ; Abramov, Mikhail ; Herdewijn, Piet ; Holliger, Philipp
Publisher:London: Nature Publishing Group UK
Journal title:Nature chemistry, 2023-01, Vol.15 (1), p.91-100
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Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket – targeting P-pocket by fragment screening
Author / Creator:Singh, Abhimanyu K. ; Martinez, Sergio E. ; Gu, Weijie ; Nguyen, Hoai ; Schols, Dominique ; Herdewijn, Piet ; De Jonghe, Steven ; Das, Kalyan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-12, Vol.12 (1), p.7127-10, Article 7127
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Random-sequence genetic oligomer pools display an innate potential for ligation and recombination
Author / Creator:Mutschler, Hannes ; Taylor, Alexander I ; Porebski, Benjamin T ; Lightowlers, Alice ; Houlihan, Gillian ; Abramov, Mikhail ; Herdewijn, Piet ; Holliger, Philipp
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2018-11, Vol.7
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ArticlesPeer ReviewedFull Text
3-nitropyridine analogues as novel microtubule-targeting agents
Author / Creator:Herman, Jean ; Vanstreels, Els ; Bardiot, Dorothée ; Prota, Andrea E. ; Gaillard, Natacha ; Gao, Ling-Jie ; Vercruysse, Thomas ; Persoons, Leentje ; Daems, Tinne ; Waer, Mark ; Herdewijn, Piet ; Louat, Thierry ; Steinmetz, Michel O. ; De Jonghe, Steven ; Sprangers, Ben ; Daelemans, Dirk
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-11, Vol.19 (11), p.e0307153
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ArticlesPeer ReviewedFull Text
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors
Author / Creator:Gao, Shenghua ; Song, Letian ; Xu, Hongtao ; Fikatas, Antonios ; Oeyen, Merel ; De Jonghe, Steven ; Zhao, Fabao ; Jing, Lanlan ; Jochmans, Dirk ; Vangeel, Laura ; Cheng, Yusen ; Kang, Dongwei ; Neyts, Johan ; Herdewijn, Piet ; Schols, Dominique ; Zhan, Peng ; Liu, Xinyong
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.160
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ArticlesPeer ReviewedFull Text
Phosphorus Pentachloride Promoted gem-Dichlorination of 2′- and 3′-Deoxynucleosides
Author / Creator:Da Paixao Soares, Fabio ; Groaz, Elisabetta ; Herdewijn, Piet
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-06, Vol.23 (6), p.1457
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A PKS/NRPS/FAS Hybrid Gene Cluster from Serratia plymuthica RVH1 Encoding the Biosynthesis of Three Broad Spectrum, Zeamine-Related Antibiotics
Author / Creator:Masschelein, Joleen ; Mattheus, Wesley ; Gao, Ling-Jie ; Moons, Pieter ; Van Houdt, Rob ; Uytterhoeven, Birgit ; Lamberigts, Chris ; Lescrinier, Eveline ; Rozenski, Jef ; Herdewijn, Piet ; Aertsen, Abram ; Michiels, Chris ; Lavigne, Rob
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-01, Vol.8 (1), p.e54143
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ArticlesPeer ReviewedFull Text
O -2-Alkylated Cytosine Acyclic Nucleoside Phosphonamidate Prodrugs Display Pan-Genotype Antiviral Activity against African Swine Fever Virus
Author / Creator:Goulding, Leah V. ; Kiss, Eleonóra ; Vrancken, Robert ; Goris, Nesya ; Luo, Min ; Groaz, Elisabetta ; Herdewijn, Piet ; Dixon, Linda
Publisher:United States: American Society for Microbiology
Journal title:mSphere, 2022-12, Vol.7 (6), p.e0037822
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ArticlesPeer ReviewedFull Text
Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution
Author / Creator:Samson, Camille ; Legrand, Pierre ; Tekpinar, Mustafa ; Rozenski, Jef ; Abramov, Mikhail ; Holliger, Philipp ; Pinheiro, Vitor ; Herdewijn, Piet ; Delarue, Marc
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2020-12, Vol.10 (12), p.1647
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ArticlesPeer ReviewedFull Text
Subnanomolar MAS-related G protein-coupled receptor-X2/B2 antagonists with efficacy in human mast cells and disease models
Author / Creator:Al Hamwi, Ghazl ; Alnouri, Mohamad Wessam ; Verdonck, Sven ; Leonczak, Piotr ; Chaki, Shaswati ; Frischbutter, Stefan ; Kolkhir, Pavel ; Matthey, Michaela ; Kopp, Constantin ; Bednarski, Marek ; Riedel, Yvonne K. ; Marx, Daniel ; Clemens, Sophie ; Namasivayam, Vigneshwaran ; Gattner, Susanne ; Thimm, Dominik ; Sylvester, Katharina ; Wolf, Katharina ; Kremer, Andreas E. ; De Jonghe, Steven ; Wenzel, Daniela ; Kotańska, Magdalena ; Ali, Hydar ; Herdewijn, Piet ; Müller, Christa E.
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2025-04, Vol.10 (1), p.128-17, Article 128
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ArticlesPeer ReviewedFull Text
Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins
Author / Creator:Cremonez, Caroline ; Maiti, Mohitosh ; Peigneur, Steve ; Cassoli, Juliana ; Dutra, Alexandre ; Waelkens, Etienne ; Lescrinier, Eveline ; Herdewijn, Piet ; De Lima, Maria ; Pimenta, Adriano ; Arantes, Eliane ; Tytgat, Jan
Publisher:Switzerland: MDPI AG
Journal title:Toxins, 2016-09, Vol.8 (10), p.288-288
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ArticlesPeer ReviewedFull Text
Incorporation of Amino Acids with Long-Chain Terminal Olefins into Proteins
Author / Creator:Exner, Matthias ; Köhling, Sebastian ; Rivollier, Julie ; Gosling, Sandrine ; Srivastava, Puneet ; Palyancheva, Zheni ; Herdewijn, Piet ; Heck, Marie-Pierre ; Rademann, Jörg ; Budisa, Nediljko
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2016-02, Vol.21 (3), p.287-287
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A Simplified and Standardized Polymerase Chain Reaction Format for the Diagnosis of Leishmaniasis
Author / Creator:Deborggraeve, Stijn ; Laurent, Thierry ; Espinosa, Diego ; Van der Auwera, Gert ; Mbuchi, Margaret ; Wasunna, Monique ; El-Safi, Sayda ; Al-Basheer, Ahmed Almustafa ; Arévalo, Jorge ; Miranda-Verástegui, César ; Leclipteux, Thierry ; Mertens, Pascal ; Dujardin, Jean-Claude ; Herdewijn, Piet ; Büscher, Philippe
Publisher:Chicago, IL: The University of Chicago Press
Journal title:The Journal of infectious diseases, 2008-11, Vol.198 (10), p.1565-1572
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Phenolic profiling of caffeic acid O-methyltransferase-deficient poplar reveals novel benzodioxane oligolignols
Author / Creator:Morreel, K ; Ralph, J ; Lu, F ; Goeminne, G ; Busson, R ; Herdewijn, P ; Goeman, J.L ; Eycken, J. van der ; Boerjan, W ; Messens, E
Publisher:Rockville, MD: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2004-12, Vol.136 (4), p.4023-4036
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T. cruzi OligoC-TesT: A Simplified and Standardized Polymerase Chain Reaction Format for Diagnosis of Chagas Disease
Author / Creator:Deborggraeve, Stijn ; Coronado, Ximena ; Solari, Aldo ; Zulantay, Ines ; Apt, Werner ; Mertens, Pascal ; Laurent, Thierry ; Leclipteux, Thierry ; Stessens, Tim ; Dujardin, Jean-Claude ; Herdewijn, Piet ; Büscher, Philippe
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2009-06, Vol.3 (6), p.e450-e450
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ArticlesPeer ReviewedFull Text
Catalysts from synthetic genetic polymers
Author / Creator:Taylor, Alexander I. ; Pinheiro, Vitor B. ; Smola, Matthew J. ; Morgunov, Alexey S. ; Peak-Chew, Sew ; Cozens, Christopher ; Weeks, Kevin M. ; Herdewijn, Piet ; Holliger, Philipp
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-02, Vol.518 (7539), p.427-430
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Origin of Life: Chemical Approach
Author / Creator:Morowitz, Harold
Publisher:Baltimore: The University of Chicago Press
Journal title:The Quarterly Review of Biology, 2009, Vol.84 (1), p.106-106
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ArticlesPeer ReviewedFull Text
Selection of An Unnatural Peptide Library For dsDNA Binding
Author / Creator:Zhang, Zhenyu ; Herdewijn, Piet
Publisher:Schiphol: Bentham Science Publishers Ltd
Journal title:Current medicinal chemistry, 2001-04, Vol.8 (5), p.517-531
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Showing 1 to 20 of 45 results

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Synthetic Genetic Polymers Capable of Heredity and Evolution

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Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects

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A two-residue nascent-strand steric gate controls synthesis of 2′-O-methyl- and 2′-O-(2-methoxyethyl)-RNA

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Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket – targeting P-pocket by fragment screening

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Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

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3-nitropyridine analogues as novel microtubule-targeting agents

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Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors

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Phosphorus Pentachloride Promoted gem-Dichlorination of 2′- and 3′-Deoxynucleosides

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A PKS/NRPS/FAS Hybrid Gene Cluster from Serratia plymuthica RVH1 Encoding the Biosynthesis of Three Broad Spectrum, Zeamine-Related Antibiotics

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O -2-Alkylated Cytosine Acyclic Nucleoside Phosphonamidate Prodrugs Display Pan-Genotype Antiviral Activity against African Swine Fever Virus

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Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution

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Subnanomolar MAS-related G protein-coupled receptor-X2/B2 antagonists with efficacy in human mast cells and disease models

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Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

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Incorporation of Amino Acids with Long-Chain Terminal Olefins into Proteins

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A Simplified and Standardized Polymerase Chain Reaction Format for the Diagnosis of Leishmaniasis

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Phenolic profiling of caffeic acid O-methyltransferase-deficient poplar reveals novel benzodioxane oligolignols

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T. cruzi OligoC-TesT: A Simplified and Standardized Polymerase Chain Reaction Format for Diagnosis of Chagas Disease

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Catalysts from synthetic genetic polymers

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Origin of Life: Chemical Approach

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Selection of An Unnatural Peptide Library For dsDNA Binding

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