Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and...
Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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If and how proteasomes catalyze not only peptide hydrolysis but also peptide splicing is an open question that has divided the scientific community. The debate has so far been based on immunopeptidomics, in vitro digestions of synthetic polypeptides as well as ex vivo and in vivo experiments, which could only indirectly describe proteasome-catalyze...
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Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing
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TN_cdi_doaj_primary_oai_doaj_org_article_b17003d64f9544af818720977eafb74a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b17003d64f9544af818720977eafb74a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-45339-3
