TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcript...
TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcription
About this item
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Author / Creator
Yu, Jin-mei , Sun, Wei , Wang, Zhen-he , Liang, Xiao , Hua, Fang , Li, Ke , Lv, Xiao-xi , Zhang, Xiao-wei , Liu, Yu-ying , Yu, Jiao-jiao , Liu, Shan-shan , Shang, Shuang , Wang, Feng , Yang, Zhao-na , Zhao, Chen-xi , Hou, Xue-ying , Li, Ping-ping , Huang, Bo , Cui, Bing and Hu, Zhuo-Wei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The existence of breast cancer stem cells (BCSCs) is a major reason underlying cancer metastasis and recurrence after chemotherapy and radiotherapy. Targeting BCSCs may ameliorate breast cancer relapse and therapy resistance. Here we report that expression of the pseudokinase Tribble 3 (TRIB3) positively associates with breast cancer stemness and p...
Alternative Titles
Full title
TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcription
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b1e7a79e5d3d4b7f8ef165185b467013
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b1e7a79e5d3d4b7f8ef165185b467013
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13700-6
