A Comparison of Sanger Sequencing and Amplicon-Based Next Generation Sequencing Approaches for the D...
A Comparison of Sanger Sequencing and Amplicon-Based Next Generation Sequencing Approaches for the Detection of HIV-1 Drug Resistance Mutations
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Background: Next-generation sequencing (NGS) kits are needed to finalise the transition from Sanger sequencing to NGS in HIV-1 genotypic drug resistance testing. Materials and Methods: We compared a homemade NGS amplicon-based protocol and the AD4SEQ HIV-1 Solution v2 (AD4SEQ) NGS kit from Arrow Diagnostics for identifying resistance-associated mut...
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A Comparison of Sanger Sequencing and Amplicon-Based Next Generation Sequencing Approaches for the Detection of HIV-1 Drug Resistance Mutations
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TN_cdi_doaj_primary_oai_doaj_org_article_b200756fe87d413595e552033bdd3b00
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b200756fe87d413595e552033bdd3b00
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ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v16091465