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Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge
Author / Creator:Picarazzi, Francesca ; Vicenti, Ilaria ; Saladini, Francesco ; Zazzi, Maurizio ; Mori, Mattia
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-12, Vol.25 (23), p.5695
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Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents
Author / Creator:Brai, Annalaura ; Fazi, Roberta ; Tintori, Cristina ; Zamperini, Claudio ; Bugli, Francesca ; Sanguinetti, Maurizio ; Stigliano, Egidio ; Esté, José ; Badia, Roger ; Franco, Sandra ; Martinez, Miguel A. ; Martinez, Javier P. ; Meyerhans, Andreas ; Saladini, Francesco ; Zazzi, Maurizio ; Garbelli, Anna ; Maga, Giovanni ; Botta, Maurizio
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (19), p.5388-5393
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Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X
Author / Creator:Brai, Annalaura ; Ronzini, Stefania ; Riva, Valentina ; Botta, Lorenzo ; Zamperini, Claudio ; Borgini, Matteo ; Trivisani, Claudia Immacolata ; Garbelli, Anna ; Pennisi, Carla ; Boccuto, Adele ; Saladini, Francesco ; Zazzi, Maurizio ; Maga, Giovanni ; Botta, Maurizio
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-11, Vol.24 (21), p.3988
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External quality assessment of HIV-1 DNA quantification assays used in the clinical setting in Italy
Author / Creator:Vicenti, Ilaria ; Dragoni, Filippo ; Giannini, Alessia ; Casabianca, Anna ; Lombardi, Francesca ; Di Sante, Laura ; Turriziani, Ombretta ; Racca, Sara ; Paolucci, Stefania ; Lai, Alessia ; Bon, Isabella ; Abbate, Isabella ; Rozera, Gabriella ; Belmonti, Simone ; Scutari, Rossana ; Alteri, Claudia ; Saladini, Francesco ; Zazzi, Maurizio
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-02, Vol.12 (1), p.3291-11, Article 3291
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A Comparison of Sanger Sequencing and Amplicon-Based Next Generation Sequencing Approaches for the Detection of HIV-1 Drug Resistance Mutations
Author / Creator:Biba, Camilla ; Fiaschi, Lia ; Varasi, Ilenia ; Paletti, Chiara ; Bartolini, Niccolò ; Zazzi, Maurizio ; Vicenti, Ilaria ; Saladini, Francesco
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2024-09, Vol.16 (9), p.1465
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In Vitro Combinatorial Activity of Direct Acting Antivirals and Monoclonal Antibodies against the Ancestral B.1 and BQ.1.1 SARS-CoV-2 Viral Variants
Author / Creator:Fiaschi, Lia ; Biba, Camilla ; Varasi, Ilenia ; Bartolini, Niccolò ; Paletti, Chiara ; Giammarino, Federica ; Saladini, Francesco ; Zazzi, Maurizio ; Vicenti, Ilaria
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2024-01, Vol.16 (2), p.168
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In Vitro Anti-SARS-CoV-2 Activity of Selected Metal Compounds and Potential Molecular Basis for Their Actions Based on Computational Study
Author / Creator:Cirri, Damiano ; Marzo, Tiziano ; Tolbatov, Iogann ; Marrone, Alessandro ; Saladini, Francesco ; Vicenti, Ilaria ; Dragoni, Filippo ; Boccuto, Adele ; Messori, Luigi
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2021-12, Vol.11 (12), p.1858
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Comparison of Different HIV-1 Resistance Interpretation Tools for Next-Generation Sequencing in Italy
Author / Creator:Armenia, Daniele ; Carioti, Luca ; Micheli, Valeria ; Bon, Isabella ; Allice, Tiziano ; Bonura, Celestino ; Bruzzone, Bianca ; Bracchitta, Fiorenza ; Cerutti, Francesco ; Giammanco, Giovanni Maurizio ; Stefanelli, Federica ; Bonifacio, Maria Addolorata ; Bertoli, Ada ; Vatteroni, Marialinda ; Ibba, Gabriele ; Novazzi, Federica ; Lipsi, Maria Rosaria ; Cuomo, Nunzia ; Vicenti, Ilaria ; Ceccherini-Silberstein, Francesca ; Rossetti, Barbara ; Bezenchek, Antonia ; Saladini, Francesco ; Zazzi, Maurizio ; Santoro, Maria Mercedes
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2024-09, Vol.16 (9), p.1422
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Potential role of doravirine for the treatment of HIV-1-infected persons with transmitted drug resistance
Author / Creator:Rhee, Soo-Yon ; Schapiro, Jonathan M. ; Saladini, Francesco ; Zazzi, Maurizio ; Khoo, Saye ; Shafer, Robert W.
Publisher:England: BioMed Central Ltd
Journal title:AIDS research and therapy, 2023-02, Vol.20 (1), p.8-7, Article 8
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Molecular Epidemiology of HIV-1 in Eastern Europe and Russia
Author / Creator:van de Klundert, Maarten A. A. ; Antonova, Anastasiia ; Di Teodoro, Giulia ; Ceña Diez, Rafael ; Chkhartishvili, Nikoloz ; Heger, Eva ; Kuznetsova, Anna ; Lebedev, Aleksey ; Narayanan, Aswathy ; Ozhmegova, Ekaterina ; Pronin, Alexander ; Shemshura, Andrey ; Tumanov, Alexandr ; Pfeifer, Nico ; Kaiser, Rolf ; Saladini, Francesco ; Zazzi, Maurizio ; Incardona, Francesca ; Bobkova, Marina ; Sönnerborg, Anders
Publisher:Basel: MDPI AG
Journal title:Viruses, 2022-09, Vol.14 (10), p.2099
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HIV-1 A1 Subtype Epidemic in Italy Originated from Africa and Eastern Europe and Shows a High Frequency of Transmission Chains Involving Intravenous Drug Users
Author / Creator:Lai, Alessia ; Bozzi, Giorgio ; Franzetti, Marco ; Binda, Francesca ; Simonetti, Francesco R. ; De Luca, Andrea ; Micheli, Valeria ; Meraviglia, Paola ; Bagnarelli, Patrizia ; Di Biagio, Antonio ; Monno, Laura ; Saladini, Francesco ; Zazzi, Maurizio ; Zehender, Gianguglielmo ; Ciccozzi, Massimo ; Balotta, Claudia
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016, Vol.11 (1), p.e0146097
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Cohort profile: A European multidisciplinary network for the fight against HIV drug resistance (EuResist Network)
Author / Creator:Rossetti, Barbara ; Incardona, Francesca ; Di Teodoro, Giulia ; Mommo, Chiara ; Saladini, Francesco ; Kaiser, Rolf ; Sönnerborg, Anders ; Lengauer, Thomas ; Zazzi, Maurizio
Publisher:Basel, Switzerland: MDPI
Journal title:Tropical medicine and infectious disease, 2023-04, Vol.8 (5), p.1-13
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Use of Peripheral Blood DNA for Genotype Antiretroviral Resistance Testing in Drug-Naive HIV-Infected Subjects
Author / Creator:Vicenti, Ilaria ; Razzolini, Francesca ; Saladini, Francesco ; Romano, Laura ; Zazzi, Maurizio
Publisher:Chicago, IL: The University of Chicago Press
Journal title:Clinical infectious diseases, 2007-06, Vol.44 (12), p.1657-1661
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Role of phenotypic investigation in the era of routine genotypic HIV-1 drug resistance testing
Author / Creator:Saladini, Francesco ; Vicenti, Ilaria
Publisher:London: Future Medicine Ltd
Journal title:Future virology, 2016-11, Vol.11 (11), p.731-744
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Sofosbuvir Selects for Drug-Resistant Amino Acid Variants in the Zika Virus RNA-Dependent RNA-Polymerase Complex In Vitro
Author / Creator:Boccuto, Adele ; Dragoni, Filippo ; Picarazzi, Francesca ; Lai, Alessia ; Della Ventura, Carla ; Veo, Carla ; Giammarino, Federica ; Saladini, Francesco ; Zehender, Gianguglielmo ; Zazzi, Maurizio ; Mori, Mattia ; Vicenti, Ilaria
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-03, Vol.22 (5), p.2670
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A novel methodology for large-scale phylogeny partition
Author / Creator:Prosperi, Mattia C.F. ; Ciccozzi, Massimo ; Fanti, Iuri ; Saladini, Francesco ; Pecorari, Monica ; Borghi, Vanni ; Di Giambenedetto, Simona ; Bruzzone, Bianca ; Capetti, Amedeo ; Vivarelli, Angela ; Rusconi, Stefano ; Re, Maria Carla ; Gismondo, Maria Rita ; Sighinolfi, Laura ; Gray, Rebecca R. ; Salemi, Marco ; Zazzi, Maurizio ; De Luca, Andrea
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2011-05, Vol.2 (1), p.321, Article 321
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Impact of the M184V Resistance Mutation on Virological Efficacy and Durability of Lamivudine-Based Dual Antiretroviral Regimens as Maintenance Therapy in Individuals With Suppressed HIV-1 RNA: A Cohor...
Author / Creator:Gagliardini, Roberta ; Ciccullo, Arturo ; Borghetti, Alberto ; Maggiolo, Franco ; Bartolozzi, Dario ; Borghi, Vanni ; Pecorari, Monica ; Di Biagio, Antonio ; Callegaro, Anna Paola ; Bruzzone, Bianca ; Saladini, Francesco ; Paolucci, Stefania ; Maserati, Renato ; Zazzi, Maurizio ; Di Giambenedetto, Simona ; De Luca, Andrea ; Mellace, Vincenzo ; Capetti, Amedeo ; Rita Gismondo, Maria ; Luisa Biondi, Maria ; Mussini, Cristina ; Pecorari, Monica ; Gianotti, Nicola ; Sacchini, Daria ; Parruti, Giustino ; Polilli, Ennio ; Baldelli, Franco ; Zanussi, Stefania ; Nerli, Alessandro ; Lenzi, Lucia ; Calzetti, Carlo ; Vivarelli, Angela ; Maserati, Renato ; Baldanti, Fausto ; Poletti, Federica ; Mondino, Vincenzo ; Malena, Marina ; Cascio, Antonio ; Filice, Gaetano ; Magnani, Giacomo ; Zerbini, Alessandro ; Lombardi, Francesca ; Di Giambenedetto, Simona ; Andreoni, Massimo ; Montano, Marco ; Vullo, Vincenzo ; Turriziani, Ombretta ; Zazzi, Maurizio ; Gonnelli, Angela ; De Luca, Andrea ; Boeri, Enzo ; Bonora, Stefano ; Ghisetti, Valeria ; Francisci, Daniela ; Grossi, Paolo ; Bagnarelli, Patrizia ; Butini, Luca ; del Gobbo, Romana ; Giacometti, Andrea ; Tacconi, Danilo ; Monno, Laura ; Punzi, Grazia ; Callegaro, Annapaola ; Maggiolo, Franco ; Zoncada, Alessia ; Paolini, Elisabetta ; Sighinolfi, Laura ; Colao, Grazia ; Corsi, Paola ; Blanc, Pierluigi ; Galli, Luisa ; Meraviglia, Paola ; Tosti, Andrea ; Bruzzone, Bianca ; Setti, Maurizio ; Penco, Giovanni ; Di Biagio, Antonio ; Nencioni, Cesira ; Pardelli, Riccardo ; Arcidiacono, Irene ; Degiuli, Alberto ; De Gennaro, Michele ; Soria, Alessandro ; Focà, Alfredo ; Surace, Latella ; Cosco, Lucio ; Malandrin, Sergio ; Milini, Paola ; Cicconi, Paola ; Rusconi, Stefano ; Micheli, Valeria
Publisher:United States: Oxford University Press
Journal title:Open forum infectious diseases, 2018-06, Vol.5 (6), p.ofy113
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Stability of unfrozen whole blood DNA for remote genotypic analysis of HIV-1 coreceptor tropism
Author / Creator:Meini, Genny ; Materazzi, Angelo ; Saladini, Francesco ; Rosi, Andrea ; Vicenti, Ilaria ; Mancini, Michele ; Pirazzoli, Antonella ; Caudai, Cinzia ; Zazzi, Maurizio
Publisher:England: BioMed Central Ltd
Journal title:BMC infectious diseases, 2013-10, Vol.13 (1), p.508-508, Article 508
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Two Distinct Hepatitis C Virus Genotype 1a Clades Have Different Geographical Distribution and Association With Natural Resistance to NS3 Protease Inhibitors
Author / Creator:De Luca, Andrea ; Di Giambenedetto, Simona ; Lo Presti, Alessandra ; Sierra, Saleta ; Prosperi, Mattia ; Cella, Eleonora ; Giovanetti, Marta ; Torti, Carlo ; Caudai, Cinzia ; Vicenti, Ilaria ; Saladini, Francesco ; Almi, Paolo ; Grima, Pierfrancesco ; Blanc, Pierluigi ; Fabbiani, Massimiliano ; Rossetti, Barbara ; Gagliardini, Roberta ; Kaiser, Rolf ; Ciccozzi, Massimo ; Zazzi, Maurizio
Publisher:United States: Oxford University Press
Journal title:Open forum infectious diseases, 2015-04, Vol.2 (2), p.ofv043
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Identification of a Possible Ancestor of the Subtype A1 HIV Type 1 Variant Circulating in the Former Soviet Union
Author / Creator:Riva, Chiara ; Romano, Laura ; Saladini, Francesco ; Lai, Alessia ; Carr, Jean K. ; Francisci, Daniela ; Balotta, Claudia ; Zazzi, Maurizio
Publisher:Larchmont, NY: Liebert
Journal title:AIDS research and human retroviruses, 2008-10, Vol.24 (10), p.1319-1325
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Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge

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Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents

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Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X

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External quality assessment of HIV-1 DNA quantification assays used in the clinical setting in Italy

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A Comparison of Sanger Sequencing and Amplicon-Based Next Generation Sequencing Approaches for the Detection of HIV-1 Drug Resistance Mutations

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In Vitro Combinatorial Activity of Direct Acting Antivirals and Monoclonal Antibodies against the Ancestral B.1 and BQ.1.1 SARS-CoV-2 Viral Variants

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In Vitro Anti-SARS-CoV-2 Activity of Selected Metal Compounds and Potential Molecular Basis for Their Actions Based on Computational Study

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Comparison of Different HIV-1 Resistance Interpretation Tools for Next-Generation Sequencing in Italy

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Potential role of doravirine for the treatment of HIV-1-infected persons with transmitted drug resistance

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Molecular Epidemiology of HIV-1 in Eastern Europe and Russia

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HIV-1 A1 Subtype Epidemic in Italy Originated from Africa and Eastern Europe and Shows a High Frequency of Transmission Chains Involving Intravenous Drug Users

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Cohort profile: A European multidisciplinary network for the fight against HIV drug resistance (EuResist Network)

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Use of Peripheral Blood DNA for Genotype Antiretroviral Resistance Testing in Drug-Naive HIV-Infected Subjects

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Role of phenotypic investigation in the era of routine genotypic HIV-1 drug resistance testing

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Sofosbuvir Selects for Drug-Resistant Amino Acid Variants in the Zika Virus RNA-Dependent RNA-Polymerase Complex In Vitro

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A novel methodology for large-scale phylogeny partition

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Impact of the M184V Resistance Mutation on Virological Efficacy and Durability of Lamivudine-Based Dual Antiretroviral Regimens as Maintenance Therapy in Individuals With Suppressed HIV-1 RNA: A Cohor...

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Stability of unfrozen whole blood DNA for remote genotypic analysis of HIV-1 coreceptor tropism

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Two Distinct Hepatitis C Virus Genotype 1a Clades Have Different Geographical Distribution and Association With Natural Resistance to NS3 Protease Inhibitors

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Identification of a Possible Ancestor of the Subtype A1 HIV Type 1 Variant Circulating in the Former Soviet Union

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