Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axi...
Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axis as a Novel Module for Targeted Intervention
About this item
Full title
Author / Creator
Youhanna, Sonia , Kemas, Aurino M. , Wright, Shane C. , Zhong, Yi , Klumpp, Britta , Klein, Kathrin , Motso, Aikaterini , Michel, Maurice , Ziegler, Nicole , Shang, Mingmei , Sabatier, Pierre , Kannt, Aimo , Sheng, Hongda , Oliva‐Vilarnau, Nuria , Büttner, Florian A. , Seashore‐Ludlow, Brinton , Schreiner, Jonas , Windbergs, Maike , Cornillet, Martin , Björkström, Niklas K. , Hülsmeier, Andreas J. , Hornemann, Thorsten , Olsen, Jesper V. , Wang, Yi , Gramignoli, Roberto , Sundström, Michael and Lauschke, Volker M.
Publisher
Germany: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
Germany: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Metabolic dysfunction‐associated steatohepatitis (MASH) is a leading cause of chronic liver disease with few therapeutic options. To narrow the translational gap in the development of pharmacological MASH treatments, a 3D liver model from primary human hepatocytes and non‐parenchymal cells derived from patients with histologically confirmed MASH wa...
Alternative Titles
Full title
Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axis as a Novel Module for Targeted Intervention
Authors, Artists and Contributors
Author / Creator
Kemas, Aurino M.
Wright, Shane C.
Zhong, Yi
Klumpp, Britta
Klein, Kathrin
Motso, Aikaterini
Michel, Maurice
Ziegler, Nicole
Shang, Mingmei
Sabatier, Pierre
Kannt, Aimo
Sheng, Hongda
Oliva‐Vilarnau, Nuria
Büttner, Florian A.
Seashore‐Ludlow, Brinton
Schreiner, Jonas
Windbergs, Maike
Cornillet, Martin
Björkström, Niklas K.
Hülsmeier, Andreas J.
Hornemann, Thorsten
Olsen, Jesper V.
Wang, Yi
Gramignoli, Roberto
Sundström, Michael
Lauschke, Volker M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b218a152bada4f5f821eb7759449ee03
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b218a152bada4f5f821eb7759449ee03
Other Identifiers
ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202407572
