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The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human b...

The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human b...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b334ddd2966948df88ef0d2a29430da2

The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells

About this item

Full title

The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells

Publisher

England: BioMed Central Ltd

Journal title

Fluids and barriers of the CNS, 2024-05, Vol.21 (1), p.39-39, Article 39

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Triptans are anti-migraine drugs with a potential central site of action. However, it is not known to what extent triptans cross the blood-brain barrier (BBB). The aim of this study was therefore to determine if triptans pass the brain capillary endothelium and investigate the possible underlying mechanisms with focus on the involvement of the puta...

Alternative Titles

Full title

The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b334ddd2966948df88ef0d2a29430da2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b334ddd2966948df88ef0d2a29430da2

Other Identifiers

ISSN

2045-8118

E-ISSN

2045-8118

DOI

10.1186/s12987-024-00544-6

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