Metabolomic analyses uncover an inhibitory effect of niclosamide on mitochondrial membrane potential...
Metabolomic analyses uncover an inhibitory effect of niclosamide on mitochondrial membrane potential in cholangiocarcinoma cells
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San Diego: PeerJ. Ltd
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English
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San Diego: PeerJ. Ltd
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Background Niclosamide is an oral anthelminthic drug that has been used for treating tapeworm infections. Its mechanism involves the disturbance of mitochondrial membrane potential that in turn inhibits oxidative phosphorylation leading to ATP depletion. To date, niclosamide has been validated as the potent anti-cancer agent against several cancers...
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Metabolomic analyses uncover an inhibitory effect of niclosamide on mitochondrial membrane potential in cholangiocarcinoma cells
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TN_cdi_doaj_primary_oai_doaj_org_article_b3670b10c86940cf978c7d275eec5e82
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b3670b10c86940cf978c7d275eec5e82
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2167-8359
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2167-8359
DOI
10.7717/peerj.16512
