Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucl...
Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Expansions of CAG/CTG trinucleotide repeats in DNA are the cause of at least 17 degenerative human disorders, including Huntington’s Disease. Repeat instability is thought to occur via the formation of intrastrand hairpins during replication, repair, recombination, and transcription though relatively little is known about their structure and dynami...
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Full title
Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
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TN_cdi_doaj_primary_oai_doaj_org_article_b4270191136b440cbcca6eb5e6840989
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4270191136b440cbcca6eb5e6840989
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20426-3
