Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congo...
Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In the mammalian host,
Trypanosoma congolense
cytoadheres, or sequesters, to the vascular endothelium. Although sequestration influences clinical outcome, disease severity and organ pathology, its determinants and mediators remain unknown. Challenges such as the variability of animal models, the only-recently developed tools to genetically ma...
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Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration
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TN_cdi_doaj_primary_oai_doaj_org_article_b46540153d414902bac05f182376943e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b46540153d414902bac05f182376943e
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-025-07739-z
