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ArticlesPeer ReviewedFull Text
Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector
Author / Creator:Mantilla, Brian S. ; Marchese, Letícia ; Casas-Sánchez, Aitor ; Dyer, Naomi A. ; Ejeh, Nicholas ; Biran, Marc ; Bringaud, Frédéric ; Lehane, Michael J. ; Acosta-Serrano, Alvaro ; Silber, Ariel M.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2017-01, Vol.13 (1), p.e1006158-e1006158
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ArticlesPeer ReviewedFull Text
Skin deep
Author / Creator:Casas-Sánchez, Aitor ; Acosta-Serrano, Álvaro
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2016-10, Vol.5
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ArticlesPeer ReviewedFull Text
Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Author / Creator:Sterkel, Marcos ; Haines, Lee R. ; Casas-Sánchez, Aitor ; Owino Adung’a, Vincent ; Vionette-Amaral, Raquel J. ; Quek, Shannon ; Rose, Clair ; Silva dos Santos, Mariana ; García Escude, Natalia ; Ismail, Hanafy M. ; Paine, Mark I. ; Barribeau, Seth M. ; Wagstaff, Simon ; MacRae, James I. ; Masiga, Daniel ; Yakob, Laith ; Oliveira, Pedro L. ; Acosta-Serrano, Álvaro
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2021-01, Vol.19 (1), p.e3000796
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ArticlesPeer ReviewedFull Text
Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus
Author / Creator:Rose, Clair ; Casas-Sánchez, Aitor ; Dyer, Naomi A. ; Solórzano, Carla ; Beckett, Alison J. ; Middlehurst, Ben ; Marcello, Marco ; Haines, Lee R. ; Lisack, Jaime ; Engstler, Markus ; Lehane, Michael J. ; Prior, Ian A. ; Acosta-Serrano, Álvaro
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2020-07, Vol.5 (7), p.909-916
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ArticlesPeer ReviewedFull Text
Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface
Author / Creator:Romero-Ramirez, Alessandra ; Casas-Sánchez, Aitor ; Autheman, Delphine ; Duffy, Craig W. ; Brandt, Cordelia ; Clare, Simon ; Harcourt, Katherine ; André, Marcos Rogério ; de Almeida Castilho Neto, Kayo José Garcia ; Teixeira, Marta M. G. ; Machado, Rosangela Zacharias ; Coombes, Janine ; Flynn, Robin J. ; Wright, Gavin J. ; Jackson, Andrew P.
Publisher:San Francisco: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2022-09, Vol.16 (9), p.e0010791-e0010791
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ArticlesPeer ReviewedFull Text
Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration
Author / Creator:Porqueddu, Teresa ; Zorrinho-Almeida, Maria ; De Niz, Mariana ; Casas-Sánchez, Aitor ; Introini, Viola ; Sanz Sender, Silvia ; Carrasqueira, Diana ; Figueiredo, Luísa M. ; Bernabeu, Maria ; Silva Pereira, Sara
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2025-02, Vol.8 (1), p.321-15, Article 321
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ArticlesPeer ReviewedFull Text
Old World cutaneous leishmaniasis treatment response varies depending on parasite species, geographical location and development of secondary infection
Author / Creator:Al-Salem, Waleed S. ; Solórzano, Carla ; Weedall, Gareth D. ; Dyer, Naomi A. ; Kelly-Hope, Louise ; Casas-Sánchez, Aitor ; Alraey, Yasser ; Alyamani, Essam J. ; Halliday, Alice ; Balghonaim, Salah M. ; Alsohibany, Khalid S. ; Alzeyadi, Zeyad ; Alzahrani, Mohamed H. ; Al-Shahrani, Ali M. ; Assiri, Abdullah M. ; Memish, Ziad ; Acosta-Serrano, Álvaro
Publisher:England: BioMed Central Ltd
Journal title:Parasites & vectors, 2019-05, Vol.12 (1), p.195-195, Article 195
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ArticlesPeer ReviewedFull Text
Association of Phlebotomus guggisbergi with Leishmania major and Leishmania tropica in a complex transmission setting for cutaneous leishmaniasis in Gilgil, Nakuru county, Kenya
Author / Creator:Owino, Barrack O. ; Matoke-Muhia, Damaris ; Alraey, Yasser ; Mwangi, Jackline Milkah ; Ingonga, Johnstone M. ; Ngumbi, Philip M. ; Casas-Sanchez, Aitor ; Acosta-Serrano, Alvaro ; Masiga, Daniel K.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2019-10, Vol.13 (10), p.e0007712
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ArticlesFull Text
The crystal structure and localization of Trypanosoma brucei invariant surface glycoproteins suggest a more permissive VSG coat in the tsetse-transmitted metacyclic stage
Author / Creator:Casas-Sanchez, Aitor ; Perally, Samirah ; Raghavendran Ramaswamy ; Haines, Lee R ; Rose, Clair ; Yunta, Cristina ; Aguilera-Flores, Marcela ; Lehane, Michael J ; Almeida, Igor C ; Boulanger, Martin J ; Acosta-Serrano, Alvaro
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-11
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ArticlesPeer ReviewedFull Text
The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite developme...
Author / Creator:Casas-Sanchez, Aitor ; Ramaswamy, Raghavendran ; Perally, Samïrah ; Haines, Lee R. ; Rose, Clair ; Aguilera-Flores, Marcela ; Portillo, Susana ; Verbeelen, Margot ; Hussain, Shahid ; Smithson, Laura ; Yunta, Cristina ; Lehane, Michael J. ; Vaughan, Sue ; van den Abbeele, Jan ; Almeida, Igor C. ; Boulanger, Martin J. ; Acosta-Serrano, Álvaro
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-03, Vol.19 (3), p.e1011269-e1011269
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ArticlesPeer ReviewedFull Text
Characterization of a novel glycosylated glutathione transferase of Onchocerca ochengi , closest relative of the human river blindness parasite
Author / Creator:Rose, Clair ; Praulins, Giorgio ; Armstrong, Stuart D. ; Casas-Sanchez, Aitor ; Davis, Jem ; Molyneux, Gemma ; Yunta, Cristina ; Stead, Zenaida ; Prescott, Mark ; Perally, Samirah ; Rutter, Anne ; Makepeace, Benjamin L. ; La Course, E. James ; Acosta-Serrano, Alvaro
Publisher:England: Cambridge University Press
Journal title:Parasitology, 2019-12, Vol.146 (14), p.1773-1784
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ArticlesFull Text
Protein N-glycosylation is essential for SARS-CoV-2 infection
Author / Creator:Casas-Sanchez, Aitor ; Romero-Ramirez, Alessandra ; Hargreaves, Eleanor ; Ellis, Cameron C ; Grajeda, Brian I ; Estevao, Igor ; Patterson, Edward I ; Hughes, Grant L ; Almeida, Igor C ; Zech, Tobias ; Acosta-Serrano, Alvaro
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-06
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ArticlesFull Text
Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells
Author / Creator:Hegde, Shivanand ; Voronin, Denis ; Casas-Sanchez, Aitor ; Saldana, Miguel A ; Heinz, Eva ; Acosta-Serrano, Alvaro ; Popov, Vsevolod L ; Chopra, Ashok K ; Hughes, Grant L
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-01
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ArticlesFull Text
Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus
Author / Creator:Rose, Clair ; Dyer, Naomi A ; Casas-Sanchez, Aitor ; Beckett, Alison J ; Solorzano, Carla ; Middlehurst, Ben ; Marcello, Marco ; Lehane, Michael J ; Prior, Ian A ; Acosta-Serrano, Alvaro
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-01
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Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector

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Skin deep

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Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis

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Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus

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Vivaxin genes encode highly immunogenic, non-variant antigens on the Trypanosoma vivax cell-surface

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Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration

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Old World cutaneous leishmaniasis treatment response varies depending on parasite species, geographical location and development of secondary infection

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Association of Phlebotomus guggisbergi with Leishmania major and Leishmania tropica in a complex transmission setting for cutaneous leishmaniasis in Gilgil, Nakuru county, Kenya

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The crystal structure and localization of Trypanosoma brucei invariant surface glycoproteins suggest a more permissive VSG coat in the tsetse-transmitted metacyclic stage

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The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite developme...

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Characterization of a novel glycosylated glutathione transferase of Onchocerca ochengi , closest relative of the human river blindness parasite

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Protein N-glycosylation is essential for SARS-CoV-2 infection

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Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells

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Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus

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