DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mou...
DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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Huntington disease (HD) is a devastating neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin gene. Disrupted cortico-striatal transmission is an early event that contributes to neuronal spine and synapse dysfunction primarily in striatal medium spiny neurons, the most vulnerable cell type in the disease, but also in neuron...
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DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_b4cb13fb61c5467bbd2761b7d6e1c14c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b4cb13fb61c5467bbd2761b7d6e1c14c
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2020.590569
