Lactate aggravates inflammation through the upregulation of ICAM-1 via GPR81-HSPA12B-mediated signal...
Lactate aggravates inflammation through the upregulation of ICAM-1 via GPR81-HSPA12B-mediated signaling in acute lung injury
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Author / Creator
Chang, Wei , Liu, Xu , Wang, Haofei , Zhu, Xingxing , Huang, Wei , Liu, Ling , Qiu, Haibo and Yang, Yi
Publisher
China: Lippincott Williams & Wilkins Ovid Technologies
Journal title
Language
English
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Publisher
China: Lippincott Williams & Wilkins Ovid Technologies
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Contents
Western blotting indicated that ICAM-1 protein expression was significantly induced in lung tissues in this mouse ALI model. [...]an in vitro experiment revealed a marked increase in ICAM-1 protein expression in vascular ECs stimulated by lactate. [...]the results showed that ALI mice pre-conditioned with 3-OBA exhibited restored HSPA12B protein ex...
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Full title
Lactate aggravates inflammation through the upregulation of ICAM-1 via GPR81-HSPA12B-mediated signaling in acute lung injury
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b52a576418fb45f293ba4dfc69d91235
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b52a576418fb45f293ba4dfc69d91235
Other Identifiers
ISSN
0366-6999,2542-5641
E-ISSN
2542-5641
DOI
10.1097/CM9.0000000000003153
