Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets
Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets
About this item
Full title
Author / Creator
Dolezalova, Nikola , Gruszczyk, Anja , Barkan, Kerry , Gamble, John A. , Galvin, Sam , Moreth, Till , O’Holleran, Kevin , Mahbubani, Krishnaa T. , Higgins, Jackie A. , Gribble, Fiona M. , Reimann, Frank , Surmacki, Jakub , Andrews, Simon , Casey, John J. , Pampaloni, Francesco , Murphy, Michael P. , Ladds, Graham , Slater, Nigel K. H. and Saeb-Parsy, Kourosh
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Cryopreservation offers the potential to increase the availability of pancreatic islets for treatment of diabetic patients. However, current protocols, which use dimethyl sulfoxide (DMSO), lead to poor cryosurvival of islets. We demonstrate that equilibration of mouse islets with small molecules in aqueous solutions can be accelerated from > 24 to...
Alternative Titles
Full title
Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets
Authors, Artists and Contributors
Author / Creator
Gruszczyk, Anja
Barkan, Kerry
Gamble, John A.
Galvin, Sam
Moreth, Till
O’Holleran, Kevin
Mahbubani, Krishnaa T.
Higgins, Jackie A.
Gribble, Fiona M.
Reimann, Frank
Surmacki, Jakub
Andrews, Simon
Casey, John J.
Pampaloni, Francesco
Murphy, Michael P.
Ladds, Graham
Slater, Nigel K. H.
Saeb-Parsy, Kourosh
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_b718aa2f9b114fbdad8edf4f86a67ef9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b718aa2f9b114fbdad8edf4f86a67ef9
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-89853-6
