Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells
Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Interleukin-15 (IL-15) is essential for the development and maintenance of natural killer (NK) cells. IL-15 activates STAT5 proteins, which can form dimers or tetramers. We previously found that NK cell numbers are decreased in
Stat5a
−
Stat5b
tetramer-deficient double knockin (DKI) mice, but the mechanism was not investigated. Here we...
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Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells
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TN_cdi_doaj_primary_oai_doaj_org_article_b737b1cb8b61414c848b3ccab3e8881b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b737b1cb8b61414c848b3ccab3e8881b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01477-5
